Results 241 to 250 of about 186,549 (302)

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Total chemical synthesis of pentameric cholera toxin subunit B.

Chem Commun (Camb)
Spaltenstein P, Scherer SR, Jones TE, Giesler RJ, Kay MS.   +4 more
europepmc   +1 more source

Development and assessment of a peptide vaccine against ovarian cancer utilizing nanoliposomes loaded with P53, WT1, and CA125 epitopes. [PDF]

J Ovarian Res
Shariati F, Hashemi M, Peyvandi M, Jebali A, Entezari M.   +4 more
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Harnessing toxin-mediated ribosome stalling as a complementary tool to annotate bacterial ORFs. [PDF]

Nucleic Acids Res
Troian EA, Barth VC, Chauhan U, Zheng H, Zhao C, Zeng J, Husson RN, Woychik NA.   +7 more
europepmc   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

The venom gland transcriptome of Tityus paraguayensis reveals a diverse array of bioactive molecules from the Brazilian Cerrado. [PDF]

PLoS One
Covali-Pontes HR, Meneguelli B, Carretone JM, Ribeiro AC, Santos ACD, Carlos TF, Chiaratti MR, Ferro M, Silva FH, Rodrigues RDS, Lucena MN.   +10 more
europepmc   +1 more source

A framework for the safety evaluation of peptides in cosmetics. [PDF]

Curr Res Toxicol
Bjerke DL, Li J, Gao Y, Hu P, Lintner K, Hakozaki T.   +5 more
europepmc   +1 more source

Molecular Basis of the Inhibition of Voltage-Gated Potassium Channel Kv1.1 by Chinese Tarantula Peptide Huwentoxin-XI. [PDF]

Toxins (Basel)
Luo X, Yin Y, Wang F, Li X, Wang S, Yang Y, Zheng C, Liu J, Deng M.   +8 more
europepmc   +1 more source

Identification of targetable epitope surfaces from the high resolution structure of the superantigen Staphylococcal enterotoxin L. [PDF]

Sci Rep
Klamm E, Curato C, Siewert K, Marino SF.
europepmc   +1 more source