Results 221 to 230 of about 183,535 (259)
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Deduction of functional peptide motifs in scorpion toxins
Journal of Peptide Science, 2006AbstractScorpion toxins are important physiological probes for characterizing ion channels. Molecular databases have limited functional annotation of scorpion toxins. Their function can be inferred by searching for conserved motifs in sequence signature databases that are derived statistically but are not necessarily biologically relevant.
Tan, P.T.J., Brusic, V., Ranganathan, S.
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Spider peptide toxins as leads for drug development
Expert Opinion on Drug Discovery, 2007Venomous animals use a highly complex cocktails of proteins, peptides and small molecules to subdue and kill their prey. As such, venoms represent highly valuable combinatorial peptide libraries, displaying an extensive range of pharmacological activities, honed by natural selection.
Escoubas, Pierre, Bosmans, Frank
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Vaccine, 1986
The role of the size of synthetic peptides in their immunological cross-reactivity with the parent native protein, was investigated using the cholera toxin system. The results show that elongation of a peptide may affect the reactivity of the antibodies it elicits in either positive or negative directions. Thus, elongation by six amino acid residues of
C O, Jacob, I, Harari, R, Arnon, M, Sela
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The role of the size of synthetic peptides in their immunological cross-reactivity with the parent native protein, was investigated using the cholera toxin system. The results show that elongation of a peptide may affect the reactivity of the antibodies it elicits in either positive or negative directions. Thus, elongation by six amino acid residues of
C O, Jacob, I, Harari, R, Arnon, M, Sela
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Peptide toxins as tools in ion channel biology
Current Opinion in Chemical BiologyAnimal venom contains ion channel-targeting peptide toxins that inflict paralysis or pain. The high specificity and potency of these toxins for their target ion channels provides enticing opportunities for their deployment as tools in channel biology.
Sucheta Bandyopadhyay +2 more
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Chemistry of the Amanita Peptide Toxins
2018Extraordinary advances in scientific methodologies during the nineteenth and twentieth centuries enabled chemists to isolate and characterize biologically active molecules from all branches of the tree of life. Biochemicals (such as DNA, RNA, proteins, and lipids) that are essential for the basic cellular processes of life are known as primary ...
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Molluscs toxin peptides in cardiovascular disease management
Natural Product ResearchThis letter emphasizes the potential of mollusc toxin peptides as innovative treatments for cardiovascular diseases (CVDs). Given the rising incidence of CVDs and the limitations of current therapies, new approaches are essential. Molluscs produce bioactive peptides that show promising anti-hypertensive, anti-thrombotic, and cardio-protective ...
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Omic Analysis of Protein and Peptide Toxins in Food
2017Food products can be contaminated by toxic proteins and peptides derived from many different flources at any stage of the production chain. Food contamination represents a major public health concern, and for this reason, monitoring of food production has become crucial for preventing food poisfining.
Ferranti Pasquale +2 more
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Efficient Chemical Synthesis and Oxidative Folding Studies of Scorpion Toxin Peptide WaTx
Acta Chimica Sinica, 2022Kewei Wang
exaly