Ventricular expression of natriuretic peptides inNpr1 −/− mice with cardiac hypertrophy and fibrosis
L. J. Ellmers +5 more
openalex +1 more source
Antimicrobial endotoxin‐neutralizing peptides promote keratinocyte migration via P2X7 receptor activation and accelerate wound healing in vivo [PDF]
Anja Pfalzgraff +6 more
openalex +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
AI-Driven Rapid Screening and Characterization of Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Peptides from Goat Blood Proteins: An Integrative <i>In Silico</i> and Experimental Strategy. [PDF]
Tan J +6 more
europepmc +1 more source
The first cryo‐EM visualization and quantification of oriented Photosystem I (PSI) on single‐layer graphene is reported. Domain‐specific covalent anchoring of PSI, with the reducing side of the biophotocatalyst toward graphene, promotes three‐fold higher anodic photocurrent generation compared to a randomly physisorbed counterpart. This approach allows
Miriam Izzo +6 more
wiley +1 more source
Characterization of the biodistribution profile of a human Dialyzable Leukocyte Extract (hDLE) by <i>in vivo</i> fluorescence imaging: a strategy to infer the ADME profile of complex multipeptide drugs. [PDF]
Fragozo A +10 more
europepmc +1 more source
Antimicrobial Peptides: Mechanisms of Action and Resistance
B. Bechinger, S. Gorr
semanticscholar +1 more source
Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments
Stéphanie M. Guéret +11 more
openalex +1 more source
Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist [PDF]
Ferenc G. Rick +12 more
openalex +1 more source
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source

