Results 121 to 130 of about 155,443 (280)
Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile
Microbial Cell, 2018 Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
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JSFA reports, EarlyView.Abstract Background Typhonium flagelliforme is a medicinal herb in the Araceae family, widely distributed in Southeast Asia. This study aimed to evaluate the effects of hydroponic and soil‐based cultivation systems on the phytochemical content and bioactivity of T. flagelliforme. Results Using liquid chromatography‐mass spectrometry (LC‐MS) analysis, 9
Yen Ning Lee +4 more
wiley +1 more source
Macromolecular Rapid Communications, EarlyView.Sulfonium‐based antimicrobial block copolymers combine an active cationic hydrophobic block with a neutral hydrophilic block to improve cytocompatibility. The hydrophobicity of the sulfonium‐based block controls the activity against S. aureus and E coli.
Sidra Kanwal +5 more
wiley +1 more source
Translation of peptidoglycan metabolites into immunotherapeutics
Clinical & Translational Immunology, 2019 The discovery of defined peptidoglycan metabolites that activate host immunity and their specific receptors has revealed fundamental insights into host–microbe recognition and afforded new opportunities for therapeutic development against infection and ...
Matthew E Griffin +3 more
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Frontiers in Microbiology, 2019 Pseudomonas aeruginosa is one of the first causes of acute nosocomial and chronic infections in patients with underlying respiratory pathologies such as cystic fibrosis (CF). It has been proposed that P.
Gabriel Torrens +8 more
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Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning
Macromolecular Rapid Communications, EarlyView.Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh +2 more
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Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, EarlyView.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Atomic-scale simulations of reactive oxygen plasma species interacting with bacterial cell walls
New Journal of Physics, 2012 In recent years there has been growing interest in the use of low-temperature atmospheric pressure plasmas for biomedical applications. Currently, however, there is very little fundamental knowledge regarding the relevant interaction mechanisms of plasma
M Yusupov +5 more
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Pest Management Science, EarlyView.Leaf age influences metabolomic profiling but not bioactivity of Eucalyptus globulus essential oils. Leaf age affects volatile levels of young and adult E. globulus oils, but not their bioactivity. Young leaf essential oil had higher contents of α‐ and β‐pinene. AEEO had higher levels of 1,8‐cineole and trans‐pinocarveol.
Mafalda Pinto +11 more
wiley +1 more source
Responsive Materials, EarlyView.We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin +3 more
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