Results 141 to 150 of about 111,225 (303)

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

open access: yesResponsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan   +8 more
wiley   +1 more source

Modular Molecular Design and Self‐Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels

open access: yesSmall, EarlyView.
Saccharide‐appended cyclic dipeptides are designed and developed as building blocks for glycosidase‐responsive supramolecular hydrogels. Their aqueous self‐assembly enables β‐galactosidase‐triggered gel‐to‐sol and neuraminidase‐triggered sol‐to‐gel transition systems, highlighting their potential as glycosidase‐responsive soft materials for biomedical ...
Shintaro Sugiura   +6 more
wiley   +1 more source

Stepwise mitochondria‐targeted photodynamic immunotherapy enabled by an outer membrane vesicles‐based nanoplatform for synergistic tumor ablation and immune reprogramming

open access: yesSmart Molecules, EarlyView.
We constructed a novel excellent photodynamic drug without heavy atoms based on the conventional BODIPY photosensitizer, and then obtained a photodynamic vesicle with efficient tumor targeting (BDPM@OMVs) by bacterial extravasation. Multiple reactive oxygen species were efficiently generated under light irradiation, and the spontaneous elimination of ...
Xiang Cheng   +11 more
wiley   +1 more source

Bacterial peptidoglycan (murein) hydrolases

open access: yes
Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan hydrolases and their cleavage sites is provided.
Charlier P, Vollmer W, Joris B, Foster S
core  

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

open access: yesThe Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo   +11 more
wiley   +1 more source

Peptidoglycan Degrading and Sensing Systems of Mycobacterium tuberculosis [PDF]

open access: yes, 2012
Mycobacterium tuberculosis (Mtb) cell wall, built on a cross-linked sugar-peptide polymer called peptidoglycan, protects the bacterial cell from adverse environments.
Prigozhin, Daniil Markovich
core  

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Effects of Live and Heat‐Treated Bifidobacterium longum CECT 7347 in Adults With Allergic Rhinitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial

open access: yesAllergy, EarlyView.
This randomized, double‐blind, placebo‐controlled trial evaluated the effects of live probiotic and HT postbiotic B. longum CECT 7347 in adults with moderate–severe allergic rhinitis. Postbiotic supplementation for 8 weeks significantly reduced CSMS and dSS, exceeding the established CSMS MCID with a 33% greater improvement, when compared to placebo ...
Ana Cardoso   +9 more
wiley   +1 more source

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli.

open access: yesPLoS Genetics
Peptidoglycan hydrolases facilitate bacterial cell wall growth by creating space for insertion of new material and allowing physical separation of daughter cells.
Víctor M Hernández-Rocamora   +13 more
doaj   +1 more source

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

open access: yesAllergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann   +19 more
wiley   +1 more source

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