Results 161 to 170 of about 147,833 (381)

The Biological Properties and Potential Interacting Proteins of d-Alanyl-d-alanine Ligase A from Mycobacterium tuberculosis

open access: yesMolecules, 2018
(1) Background: d-alanine-d-alanine ligase (DdlA), an effective target for drug development to combat against Mycobacterium tuberculosis (Mtb), which threatens human health globally, supplies a substrate of d-alanyl-d-alanine for peptidoglycan ...
Shufeng Yang   +7 more
doaj   +1 more source

Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications

open access: yesNature Communications, 2017
Bacterial cells are surrounded by a polymer known as peptidoglycan (PG), which protects the cell from changes in osmotic pressure and small molecule insults.
Hai Liang   +5 more
semanticscholar   +1 more source

Effect of peptidoglycans on erythrocyte survival

open access: yesInternational Journal of Medical Microbiology, 2009
Peptidoglycans (PGNs) from bacterial cell walls belong to 'pathogen-associated molecular patterns' (PAMP), which modify the course of an infection with bacterial pathogens. Bacterial infections may lead to anaemia, which at least partially could result from accelerated erythrocyte death.
Hasan Mahmud   +7 more
openaire   +3 more sources

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

open access: yesAdvanced Science, EarlyView.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li   +8 more
wiley   +1 more source

Deep Learning‐Assisted Rapid Bacterial Classification Based on Raman Spectroscopy of Bacteria Lysed by Acoustically Driven Fiber‐Tip Vibration

open access: yesAdvanced Science, EarlyView.
A novel acoustofluidic lysis technique based on a vibrating fiber‐tip is integrated with Raman spectroscopy and deep learning for rapid, label‐free bacterial classification. By exposing intracellular biomolecules, this method significantly enhances spectral resolution, enabling high‐accuracy classification with a 1D‐ResNet model.
Yukai Liu   +9 more
wiley   +1 more source

Determinants of Bacterial Morphology: From Fundamentals to Possibilities for Antimicrobial Targeting

open access: yesFrontiers in Microbiology, 2017
Bacterial morphology is extremely diverse. Specific shapes are the consequence of adaptive pressures optimizing bacterial fitness. Shape affects critical biological functions, including nutrient acquisition, motility, dispersion, stress resistance and ...
Muriel C. F. van Teeseling   +2 more
doaj   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

The Peptidoglycan Pattern of Staphylococcus carnosus TM300—Detailed Analysis and Variations Due to Genetic and Metabolic Influences

open access: yesAntibiotics, 2016
The Gram-positive bacterium Staphylococcus carnosus (S. carnosus) TM300 is an apathogenic staphylococcal species commonly used in meat starter cultures.
Julia Deibert   +4 more
doaj   +1 more source

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