RNAs Associated With Bacterial Outer Membrane Vesicles: Structural Insights Into Surface Composition
This work uncovers a new layer of bacterial communication. We show that RNAs, aided by the Hfq RNA‐chaperone, are not only packed inside Gram negative Outer Membrane Vesicles (OMVs) but can also be embedded in their membranes. This suggests that bacteria may use surface‐exposed RNAs to directly interact with host cells. Overall, our results broaden the
Kevin Mosca +4 more
wiley +1 more source
Targeting Bacterial Cell Wall Synthesis: Structural Insights and Emerging Therapeutic Strategies. [PDF]
Sanapalli BKR, Jones CR, Sanapalli V.
europepmc +1 more source
ABSTRACT Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global cause of death due to the pathogen's highly adaptive physiology and its ability to manipulate host immunity. Despite extensive study, our understanding of Mtb biology during infection remains incomplete, limiting the development of new diagnostics ...
José L. Serrano‐Mestre +15 more
wiley +1 more source
Unravelling the unique essential genes of <i>Streptococcus canis</i> through transposon-directed insertion-site sequencing. [PDF]
Aubry E +9 more
europepmc +1 more source
Bioanalytical TERS and Advanced Data Processing Methods
Tip‐enhanced Raman spectroscopy delivers label‐free, subnanometer vibrational imaging of biological systems. Recent advances in instrumentation, data analysis, and ambient/liquid operation enable surface‐selective mapping of molecular heterogeneity in proteins, nucleic acids, membranes, and viruses, positioning TERS as a powerful platform for nanoscale
Sarika Joshi +6 more
wiley +1 more source
Detection and identification of pathogens using agents targeting the bacterial cell wall. [PDF]
Zhydzetski A +3 more
europepmc +1 more source
A New Endolysin Lys59: A Broad-Spectrum Phage Endolysin Targeting Both Gram-Negative and Gram-Positive Bacteria. [PDF]
Zhang Y +5 more
europepmc +1 more source
SEDS glycosyltransferases in <i>E. faecalis</i> are upregulated by the CroS/R two-component system to enhance peptidoglycan synthesis during cell wall stress. [PDF]
Nelson ME +3 more
europepmc +1 more source
Substrate Specificity and Immunological Implications of <i>Cutibacterium acnes</i> Phage Endolysins. [PDF]
Bashir HH, Hasnain MA, Moon GS.
europepmc +1 more source

