Two New M23 Peptidoglycan Hydrolases With Distinct Net Charge [PDF]
Frontiers in Microbiology, 2021 Bacterial peptidoglycan hydrolases play an essential role in cell wall metabolism during bacterial growth, division, and elongation (autolysins) or in the elimination of closely related species from the same ecological niche (bacteriocins).
Alicja Wysocka +3 more
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One fold, many functions—M23 family of peptidoglycan hydrolases [PDF]
Frontiers in Microbiology, 2022 Bacterial cell walls are the guards of cell integrity. They are composed of peptidoglycan that provides rigidity to sustain internal turgor and ensures isolation from the external environment.
Alicja Razew +4 more
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Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases [PDF]
mBio, 2015 Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target.
Richard Wheeler +9 more
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Prediction of peptidoglycan hydrolases- a new class of antibacterial proteins. [PDF]
BMC Genomics, 2016 Comparison of performance of the three approaches using known 250 peptidoglycan hydrolases.
Sharma AK +4 more
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Archaea produce peptidoglycan hydrolases that kill bacteria [PDF]
PLoS BiologyThe social life of archaea is poorly understood. In particular, even though competition and conflict are common themes in microbial communities, there is scant evidence documenting antagonistic interactions between archaea and their abundant prokaryotic brethren: bacteria. Do archaea specifically target bacteria for destruction?
Romain Strock +6 more
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Phenotypic and genotypic characterization of peptidoglycan hydrolases of Lactobacillus sakei [PDF]
Journal of Advanced Research, 2016 Lactobacillus sakei, a lactic acid bacterium naturally found in fresh meat and sea products, is considered to be one of the most important bacterial species involved in meat fermentation and bio-preservation. Several enzymes of Lb.
Afef Najjari +6 more
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Peptidoglycan Hydrolases of Local Lactic Acid Bacteria from Kazakh Traditional Food [PDF]
Central Asian Journal of Global Health, 2014 Introduction: Peptidoglycan (PG) is a major component of the cell wall of Gram-positive bacteria and is essential for maintaining the integrity of the bacterial cell and its shape.
Serik Shaikhin +6 more
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Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of
Microbial Cell Factories, 2012 Background Lactobacillus plantarum is commonly used in industrial fermentation processes. Selected strains are also marketed as probiotics for their health beneficial effects.
Rolain Thomas +6 more
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Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. [PDF]
PLoS Pathogens, 2013 Peptidoglycan hydrolases are a double-edged sword. They are required for normal cell division, but when dysregulated can become autolysins lethal to bacteria.
Michael C Chao +7 more
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Regulation of peptidoglycan hydrolases: localization, abundance, and activity. [PDF]
Curr Opin Microbiol, 2023 Most bacteria are surrounded by a cell wall composed of peptidoglycan (PG) that specifies shape and protects the cell from osmotic rupture. Growth, division, and morphogenesis are intimately linked to the synthesis of this exoskeleton but also its hydrolysis. The enzymes that cleave the PG meshwork require careful control to prevent aberrant hydrolysis
Brogan AP, Rudner DZ.
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