Results 41 to 50 of about 14,172 (195)

Zymogram Assay for the Detection of Peptidoglycan Hydrolases in Streptococcus mutans

Bio-Protocol, 2013
Peptidoglycan hydrolases or autolysins are enzymes capable of cleaving covalent bonds in bacterial peptidoglycan cell wall layer. They can participate in the cell division process, in the release of turnover products from peptidoglycan during cell growth,
Delphine Dufour, Céline Lévesque
doaj   +1 more source

The Bifunctional Cell Wall Hydrolase CwlT Is Needed for Conjugation of the Integrative and Conjugative Element ICEBs1 in Bacillus subtilis and B. anthracis [PDF]

, 2014
The mobile genetic element ICEBs1 is an integrative and conjugative element (ICE) found in Bacillus subtilis. One of the ICEBs1 genes, cwlT, encodes a cell wall hydrolase with two catalytic domains, a muramidase and a peptidase.
DeWitt, Tyler, Grossman, Alan Davis
core   +1 more source

Cell morphology maintenance in Bacillus subtilis through balanced peptidoglycan synthesis and hydrolysis

Scientific Reports, 2020
The peptidoglycan layer is responsible for maintaining bacterial cell shape and permitting cell division. Cell wall growth is facilitated by peptidoglycan synthases and hydrolases and is potentially modulated by components of the central carbon ...
Jad Sassine, Joana Sousa, Michael Lalk, Richard A. Daniel, Waldemar Vollmer   +4 more
doaj   +1 more source

Diversity of the lysozyme fold: structure of the catalytic domain from an unusual endolysin encoded by phage Enc34

Scientific Reports, 2022
Endolysins are bacteriophage-encoded peptidoglycan-degrading enzymes with potential applications for treatment of multidrug-resistant bacterial infections. Hafnia phage Enc34 encodes an unusual endolysin with an N-terminal enzymatically active domain and
Elina Cernooka, Janis Rumnieks, Nikita Zrelovs, Kaspars Tars, Andris Kazaks   +4 more
doaj   +1 more source

The PECACE domain: a new family of enzymes with potential peptidoglycan cleavage activity in Gram-positive bacteria

BMC Genomics, 2005
Background The metabolism of bacterial peptidoglycan is a dynamic process, synthases and cleavage enzymes are functionally coordinated. Lytic Transglycosylase enzymes (LT) are part of multienzyme complexes which regulate bacterial division and elongation.
Di Guilmi Anne, Vernet Thierry, Dideberg Otto, Pagliero Estelle   +3 more
doaj   +1 more source

Identification of a new family of enzymes with potential -acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria [PDF]

, 2005
Background The metabolism of the rigid bacterial cell wall heteropolymer peptidoglycan is a dynamic process requiring continuous biosynthesis and maintenance involving the coordination of both lytic and synthetic enzymes.
Joel T Weadge, John M Pfeffer, Anthony J Clarke   +2 more
core   +2 more sources

DipM, a new factor required for peptidoglycan remodelling during cell division in Caulobacter crescentus [PDF]

, 2010
In bacteria, cytokinesis is dependent on lytic enzymes that facilitate remodelling of the cell wall during constriction. In this work, we identify a thus far uncharacterized periplasmic protein, DipM, that is required for cell division and polarity in ...
Aaron, Aarsman, Addinall, Arends, Bateman, Bernhardt, Bernhardt, Botstein, Bowman, Briegel, Brown, Buddelmeijer, Buist, Cohen, Costa, Dai, Dai, Den Blaauwen, Derouaux, Di Lallo, Domian, Draper, Ebersbach, Ely, Ely, Evinger, Gan, Gardy, Gerding, Gerding, Goehring, Goehring, Gueiros-Filho, Hale, Heidrich, Heidrich, Holtje, Horsburgh, Huitema, Iancu, Iversen, Joris, Judd, Karimova, Karimova, Labischinski, Lam, Li, Liu, Lutkenhaus, Margolin, Markiewicz, Martin, Mastronarde, Meisenzahl, Miller, Möll, Müller, Nierman, Ohnuma, Osawa, Osawa, Poindexter, Priyadarshini, Quardokus, Radhakrishnan, Ramadurai, Schmidt, Steen, Stephens, Suloway, Thanbichler, Thanbichler, Thanbichler, Tivol, Tsai, Uehara, Uehara, Uehara, Ursinus, Vollmer, Vollmer, Wang, Wang, Weiss, Werner, Wissel, Yamamoto, Zahrl   +88 more
core   +3 more sources

Molecular imaging of glycan chains couples cell-wall polysaccharide architecture to bacterial cell [PDF]

, 2018
Biopolymer composite cell walls maintain cell shape and resist forces in plants, fungi and bacteria. Peptidoglycan, a crucial antibiotic target and immunomodulator, performs this role in bacteria.
A Typas, AJ Meeske, AL Koch, AW Bisson-Filho, C Leung, C Paradis-Bleau, CN Takacs, D Bradley, E Rojas, EJ Hayhurst, F Wong, GJ Bean, H Harz, H Labischinski, J Heijenoort van, JC Gumbart, KC Huang, KD Young, L Furchtgott, L Gan, LT Nguyen, M Wachi, MM Farley, R Wheeler, R Wheeler, RD Turner, RD Turner, RD Turner, RD Turner, RS Dover, RW Verwer, S Hussain, S Teeffelen van, SR Clarke, T Kruse, T Pilizota, TS Ursell, V Braun, X Yang, X Yao, YF Dufrêne   +40 more
core   +2 more sources

Binding site‐shaped repeated sequences of bacterial wall peptidoglycan hydrolases [PDF]

FEBS Letters, 1994
The non‐catalytic C‐terminal regions of the N‐acetylmuramidase (lysozyme) of Clostridium acetobutylicum and N‐acetylmuramoyl(d‐lactyl)‐l‐alanine amidases CwlA of Bacillus subtilis, ORFL3 and CwlL of Bacillus licheniformis were previously reported to have similarities with the amino acid sequence of the non‐catalytic N‐terminal module of the ...
Ghuysen, Jean-Marie, Lamotte-Brasseur, Josette, Joris, Bernard, Shockman, Gérald D.   +3 more
openaire   +2 more sources

Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis

Nature Communications, 2023
The FtsEX complex regulates, directly or via a protein mediator depending on bacterial genera, peptidoglycan degradation for cell division. In mycobacteria and Gram-positive bacteria, the FtsEX system directly activates peptidoglycan-hydrolases by a ...
Jianwei Li, Xin Xu, Jian Shi, Juan A. Hermoso, Lok-To Sham, Min Luo   +5 more
doaj   +1 more source