Results 181 to 190 of about 16,142 (230)
Unlocking Enol-Ugi-Derived Conformationally Restricted Peptidomimetic Motifs. [PDF]
J Org ChemRamiro JL, Díaz J, G Neo A, F Marcos C.
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Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of <sup>18</sup>F-Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3. [PDF]
ChemMedChemHerrera-Rueda MA +4 more
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Small Molecule Protease Inhibitors as Model Peptidomimetics. [PDF]
Pharmaceuticals (Basel)Gomez-Gutierrez P, Perez JJ.
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Recognition of the CREB-Binding Protein/Mixed Lineage Leukemia Interface by Sulfonyl-γ-AApeptides: Beyond Mimicry of Mixed Lineage Leukemia. [PDF]
J Med ChemHuang B +11 more
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Minimalist and universal peptidomimetics
Chemical Society Reviews, 2011Many "new generation" peptidomimetics are designed to present amino acid side chains only; they do not have structural features that resemble peptide main chains. These types of molecules have frequently been presented in the literature as mimics of specific secondary structures.
Jing Liu, Kevin Burgess
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Molecular Informatics, 2020
AbstractEndogenous peptides as part of physiological processes are targets of interest when it comes to finding desirable therapeutics which are able to modulate molecular interactions. The major limits presented by peptides when they are used as drugs have motivated the research of the synthesis of peptidomimetics obtained through chemical ...
Cristina Tomasella +4 more
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AbstractEndogenous peptides as part of physiological processes are targets of interest when it comes to finding desirable therapeutics which are able to modulate molecular interactions. The major limits presented by peptides when they are used as drugs have motivated the research of the synthesis of peptidomimetics obtained through chemical ...
Cristina Tomasella +4 more
openaire +2 more sources
Current Opinion in Chemical Biology, 1998
Major discoveries have been made of new type-I and type-III peptidomimetic inhibitors of peptide-derived systems. Innovative reversible inhibitors of cysteine proteases and renin, and additional examples of peptidomimetic inhibitors of interleukin-1 beta-converting enzyme, neutral endopeptidase, herpes simplex virus protease, thrombin, HIV protease ...
A S, Ripka, D H, Rich
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Major discoveries have been made of new type-I and type-III peptidomimetic inhibitors of peptide-derived systems. Innovative reversible inhibitors of cysteine proteases and renin, and additional examples of peptidomimetic inhibitors of interleukin-1 beta-converting enzyme, neutral endopeptidase, herpes simplex virus protease, thrombin, HIV protease ...
A S, Ripka, D H, Rich
openaire +2 more sources
Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs
Molecules, 2017 The rapid emergence of multidrug-resistant pathogens has evolved into a global health problem as current treatment options are failing for infections caused by pan-resistant bacteria.
Natalia Molchanova +2 more
exaly +3 more sources