Results 141 to 150 of about 6,534 (185)

Determination of peptidyl dipeptidase activity in 24 bacterial species

Canadian Journal of Microbiology, 1990
Of 24 bacterial species examined for lisinopril refractive peptidyl dipeptidase activity, only 8 contained activity. Activity in Pseudomonas maltophilia was more than fourfold higher than that of any other species. Pseudomonas maltophilia may be unique among bacteria in possessing high peptidyl dipeptidase activity that is both EDTA inhibitable and ...
Joanne Stevens, Barry L Fanburg, Joseph J Lanzillo   +2 more
exaly   +3 more sources

Amino acid residues essential for catalysis by peptidyl dipeptidase-4 from pseudomonas maltophilia

Biochemical and Biophysical Research Communications, 1989
To assess residues essential for catalysis by prokaryotic peptidyl dipeptidase-4, the enzyme was subjected to chemical modification by a series of reagents. Treatment with either tetranitromethane or N-acetylimidazole abolished catalytic activity. Hydroxylamine reversed inactivation by acetylimidazole only.
Joseph J Lanzillo, Barry L Fanburg
exaly   +3 more sources

Detection of essential arginine in bacterial peptidyl dipeptidase-4: Arginine is not the anion binding site

Biochemical and Biophysical Research Communications, 1989
Peptidyl dipeptidase-4 from Pseudomonas maltophilia was modified with the arginine reagents p-hydroxyphenylglyoxal and 2,3-butanedione. The enzyme was inactivated in a pseudo-first-order manner by p-hydroxyphenylglyoxal with a half-time of 72 min. Inactivation by 2,3-butanedione was biphasic with a rapid phase followed by a slower inactivation to less ...
Joseph J Lanzillo, Barry L Fanburg
exaly   +3 more sources

A distinct peptidyl dipeptidase that degrades enkephalin: Exceptionally high activity in rabbit kidney

Life Sciences, 1981
Abstract Peptidyl dipeptidase activity distinct from the angiotensin converting enzyme (EC 3.4.15.1) was isolated from membrane fractions of rabbit kidney and lung. The enzyme cleaved Leu-enkephalin at the Gly-Phe bond, releasing Tyr-Gly-Gly and Phe-Leu, and also acted on bradykinin releasing the terminal dipeptide Phe-Arg.
M Benuck, M J Berg, N MarkS
exaly   +3 more sources

Some Characteristics of a Peptidyl Dipeptidase (Kininase II) from Rat CSF: Differential Effects of NaC1 on the Sequential Degradation Steps of Bradykinin

Journal of Neurochemistry, 1990
Abstract: Incubation of various authentic peptides with rat CSF in vitro and analysis of their products by HPLC demonstrated the presence in CSF of a peptidyl dipeptidase [peptidyl dipeptide hydrolase; angiotensin I converting enzyme (ACE); kininase II; EC 3.4.15.1] which sequentially degraded bradykinin (BK) by liberating the carboxy‐terminal ...
Shoichiro Nosaka
exaly   +2 more sources

Conversion of angiotensin-1 to angiotensin-2 by a latent endothelial cell peptidyl dipeptidase that is not angiotensin-converting enzyme

Biochemical and Biophysical Research Communications, 1986
Cultured bovine pulmonary artery endothelial cells contain a second peptidyl dipeptidase, distinct from angiotensin-converting enzyme, present in an inactive form associated with a non-dialyzable inhibitor. Partial purification by glycine affinity chromatography separates enzyme from inhibitor to yield a preparation which hydrolyzes angiotensin-1 ...
Joseph J Lanzillo, Joanne Stevens, Barry L Fanburg   +2 more
exaly   +3 more sources

Peptidyl-dipeptidase B

1998
Dietmar Schomburg, Dörte Stephan
exaly   +2 more sources

Peptidyl-dipeptidase A (invertebrate)

2004
R E Isaac
exaly   +2 more sources

Peptidyl-dipeptidase Dcp

1998
Dietmar Schomburg, Dörte Stephan
exaly   +2 more sources

Human erythrocytic prolyl endopeptidase II hydrolyzing teprotide, an inhibitor of snake venom peptidyl dipeptidase

Bulletin of Experimental Biology and Medicine, 1985
L. P. Alekseenko, V. N. Orekhovich
exaly   +2 more sources