Results 111 to 120 of about 7,517 (194)

Primer sequences and amplification summary.

open access: yes, 2013
*Tubb2a, tubulin beta 2A class IIa; B2m, β-2-Microglobulin; Actb, β-Actin; Gapdh, Glyceraldehyde-3-phospate dehydrogenase; Gusb, β-Glucuronidase; Ppia, peptidylprolyl isomerase A; Porla1a, polymerase (RNA) I polypeptide A; Rplp1, ribosomal protein, large,
Maria Luisa Paçó-Larson (407357)   +6 more
core   +1 more source

Selected GO terms associated with clusters with the largest number of proteins (stSILAC dataset).

open access: yes, 2013
Model refers to the theoretical evolution of the ratio over 3 time points (t = 0,6,20h) of GA treatment. Each model defines a cluster. PDI : protein disulphide isomerase A; PPI : peptidylprolyl isomerase; CCT : Chaperonin-Containing-TCP-1 complex.
Celine Hernandez (2234182)   +5 more
core   +1 more source

Functional role of the flexible N-terminal extension of FKBP38 in catalysis.

open access: yes, 2013
FKBP38 regulates apoptosis through unique interactions with multiple regulators including Bcl-2. Interestingly, the peptidylprolyl isomerase activity of FKBP38 is only detectable when it binds to calcium-saturated calmodulin (CaM/Ca2+).
Chia, Joel   +17 more
core   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

PPIA dictates NRF2 stability to promote lung cancer progression

open access: yesNature Communications
Nuclear factor erythroid 2-related factor 2 (NRF2) hyperactivation has been established as an oncogenic driver in a variety of human cancers, including non-small cell lung cancer (NSCLC). However, despite massive efforts, no specific therapy is currently
Weiqiang Lu   +18 more
doaj   +1 more source

PPIL2 is a target of the JAK2/STAT5 pathway and promotes myeloproliferation via degradation of p53

open access: yesThe Journal of Clinical Investigation
The activated JAK2/STAT pathway is characteristic of myeloproliferative neoplasms (MPNs). The pleckstrin 2 (PLEK2) signalosome is downstream of the JAK2/STAT5 pathway and plays an important role in MPN development.
Pan Wang   +9 more
doaj   +1 more source

Changes in mRNA levels of proinflammatory mediators in the cerebral cortex and hippocampus at 6 and 24 h after mTBI as assessed by real-time RT-PCR.

open access: yes, 2016
In these experiments, the depth of brain deformation was set at 1.5 mm. The production of proinflammatory mediators in the ipsilateral (I-Cx) versus contralateral (C-Cx) cortex, and the ipsilateral (I-Hip) versus contralateral (C-Hip) hippocampus is ...
Joanna Szmydynger-Chodobska (40715)   +3 more
core   +1 more source

Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors

open access: yes, 2016
The structure-based design and subsequent chemical synthesis of novel, urea-containing FKBP12 inhibitors are described. These compounds are shown to disrupt the cis−trans peptidylprolyl isomerase activity of FKBP12 with inhibition constants (Ki,app ...
Kathleen D. Tucker (3017934)   +15 more
core   +1 more source

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