Results 111 to 120 of about 7,517 (194)
Primer sequences and amplification summary.
*Tubb2a, tubulin beta 2A class IIa; B2m, β-2-Microglobulin; Actb, β-Actin; Gapdh, Glyceraldehyde-3-phospate dehydrogenase; Gusb, β-Glucuronidase; Ppia, peptidylprolyl isomerase A; Porla1a, polymerase (RNA) I polypeptide A; Rplp1, ribosomal protein, large,
Maria Luisa Paçó-Larson (407357) +6 more
core +1 more source
Selected GO terms associated with clusters with the largest number of proteins (stSILAC dataset).
Model refers to the theoretical evolution of the ratio over 3 time points (t = 0,6,20h) of GA treatment. Each model defines a cluster. PDI : protein disulphide isomerase A; PPI : peptidylprolyl isomerase; CCT : Chaperonin-Containing-TCP-1 complex.
Celine Hernandez (2234182) +5 more
core +1 more source
Functional role of the flexible N-terminal extension of FKBP38 in catalysis.
FKBP38 regulates apoptosis through unique interactions with multiple regulators including Bcl-2. Interestingly, the peptidylprolyl isomerase activity of FKBP38 is only detectable when it binds to calcium-saturated calmodulin (CaM/Ca2+).
Chia, Joel +17 more
core +1 more source
Deletion of a Peptidylprolyl Isomerase Gene Results in the Inability of Caldicellulosiruptor bescii To Grow on Crystalline Cellulose without Affecting Protein Glycosylation or Growth on Soluble Substrates. [PDF]
Russell JF +7 more
europepmc +1 more source
PPIA dictates NRF2 stability to promote lung cancer progression
Nuclear factor erythroid 2-related factor 2 (NRF2) hyperactivation has been established as an oncogenic driver in a variety of human cancers, including non-small cell lung cancer (NSCLC). However, despite massive efforts, no specific therapy is currently
Weiqiang Lu +18 more
doaj +1 more source
PPIL2 is a target of the JAK2/STAT5 pathway and promotes myeloproliferation via degradation of p53
The activated JAK2/STAT pathway is characteristic of myeloproliferative neoplasms (MPNs). The pleckstrin 2 (PLEK2) signalosome is downstream of the JAK2/STAT5 pathway and plays an important role in MPN development.
Pan Wang +9 more
doaj +1 more source
In these experiments, the depth of brain deformation was set at 1.5 mm. The production of proinflammatory mediators in the ipsilateral (I-Cx) versus contralateral (C-Cx) cortex, and the ipsilateral (I-Hip) versus contralateral (C-Hip) hippocampus is ...
Joanna Szmydynger-Chodobska (40715) +3 more
core +1 more source
Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors
The structure-based design and subsequent chemical synthesis of novel, urea-containing FKBP12 inhibitors are described. These compounds are shown to disrupt the cis−trans peptidylprolyl isomerase activity of FKBP12 with inhibition constants (Ki,app ...
Kathleen D. Tucker (3017934) +15 more
core +1 more source
Cyclophilin A (CYPA; peptidylprolyl isomerase A; PPIA) [PDF]
openaire +1 more source

