Results 131 to 140 of about 11,623 (233)

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans [PDF]

, 2016
Bile acids are synthesized from cholesterol in the liver and subjected to multiple metabolic biotransformations in hepatocytes, including oxidation by cytochromes P450 (CYPs) and conjugation with taurine, glycine, glucuronic acid, and sulfate.
Botham, Buffie, C. Roland Wolf, Cen Xie, Chad N. Brocker, Cheng, Cheung, Colin J. Henderson, de Aguiar Vallim, Deo, Dragin, Fedorowski, Frank J. Gonzalez, Gonzalez, Greathouse, Gu, Hardison, Hasegawa, Hirano, Hofmann, Hofmann, Inagaki, Jiang, Jiang, Jones, Katagiri, Kristopher W. Krausz, Li, Löfgren, Matsubara, Mueller, Nelson, Russell, Russell, Sayin, Scheer, Scheer, Scheer, Scheer, Seeley, Shogo Takahashi, Tanaka, Tatsuki Fukami, Thomas, van Herwaarden, Yusuke Masuo   +45 more
core   +2 more sources

Israeli acute paralysis virus infection leads to an enhanced RNA interference response and not its suppression in the bumblebee Bombus terrestris [PDF]

, 2016
RNA interference (RNAi) is the primary antiviral defense system in insects and its importance for pollinator health is indisputable. In this work, we examined the effect of Israeli acute paralysis virus (IAPV) infection on the RNAi process in the ...
Cappelle, Kaat, Dhaenens, Maarten, Meeus, Ivan, Smagghe, Guy   +3 more
core   +2 more sources

Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome [PDF]

, 2018
BACKGROUND: Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensitizing action. Gestational diabetes mellitus (GDM) is characterized by insulin resistance leading to materno-fetal hyperglycemia and detrimental birth ...
Dudenhausen, Joachim W., Henrich, Wolfgang, Melchior, Kerstin, Ott, Raffael, Plagemann, Andreas, Rancourt, Rebecca C., Schellong, Karen, Stupin, Jens H., Ziska, Thomas   +8 more
core   +2 more sources

The molecular mechanisms of peptidyl-prolyl cis/trans isomerase Pin1 and its relevance to kidney disease

Frontiers in Pharmacology
Pin1 is a member of the peptidyl-prolyl cis/trans isomerase subfamily and is widely expressed in various cell types and tissues. Alterations in Pin1 expression levels play pivotal roles in both physiological processes and multiple pathological conditions,
Shukun Wu, Yurong Zou, Xiaoqiu Tan, Shuang Yang, Shuang Yang, Tangting Chen, Jiong Zhang, Xingli Xu, Xingli Xu, Fang Wang, Wei Li   +10 more
doaj   +1 more source

Establishment of a method for detecting nucleotide polymorphism of SLC39A13 gene based on ARMS-PCR [PDF]

Journal of Hebei University of Science and Technology
In order to achieve its nucleotide polymorphism (SNP) accurate typing, this paper establishes a molecular diagnostic technique based on fluorescent quantitative PCR for accurate genotyping of the nucleotide polymorphism (SNP) at the rs755555 locus of the
Bingqian GUO, Mengyu LI, Rui WANG, Shusong WANG, Huiyong FENG, Tianming LI   +5 more
doaj   +1 more source

Editorial: Phosphorylation-Dependent Peptidyl-Prolyl Cis/Trans Isomerase PIN1

Frontiers in Cell and Developmental Biology, 2020
Jormay Lim, Tae Ho Lee, Futoshi Suizu
doaj   +1 more source

Time-dependent inhibition of peptidylprolyl cis-trans-isomerases by FK506 is probably due to cis-trans isomerization of the inhibitor's imide bond [PDF]

, 1995
Toralf Zarnt, K Lang, Helmut Burtscher, Gunter Fischer   +3 more
openalex   +1 more source

Multidimensional pan-cancer analysis reveals the impact of PPIA on tumor epigenetic modifications and immune regulation

Scientific Reports
Peptidylprolyl isomerase A (PPIA) is a key molecule involved in various biological functions and has been implicated in multiple diseases. However, the biological significance of PPIA in pan-cancer remains unclear.
Yuanqian Yao, Xueqing Gong, Hui Li
doaj   +1 more source

Reference gene selection for qRT-PCR analysis in the sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae).

PLoS ONE, 2013
BackgroundAccurate evaluation of gene expression requires normalization relative to the expression of reliable reference genes. Expression levels of "classical" reference genes can differ, however, across experimental conditions.
Rumei Li, Wen Xie, Shaoli Wang, Qingjun Wu, Nina Yang, Xin Yang, Huipeng Pan, Xiaomao Zhou, Lianyang Bai, Baoyun Xu, Xuguo Zhou, Youjun Zhang   +11 more
doaj   +1 more source

Mutations in a Peptidylprolyl-cis/trans-isomerase Gene Lead to a Defect in 3′-End Formation of a Pre-mRNA inSaccharomyces cerevisiae [PDF]

, 1999
Jean Hani, Birte Schelbert, Anne Bernhardt, Horst Domdey, Gunter Fischer, K Wiebauer, Jens‐U. Rahfeld   +6 more
openalex   +1 more source