Results 231 to 240 of about 5,830 (259)
Some of the next articles are maybe not open access.

A fluorescent peptoid pH‐sensor

Peptide Science, 2013
ABSTRACTPeptoids, N‐substituted glycine oligomers, can adopt stable three‐dimensional structures and have found diverse application as peptide surrogates and as nanomaterials. In this report, we have expanded peptoid function to include pH sensing by coupling pH‐induced peptoid conformational changes with fluorescence intensity changes.
Amelia A, Fuller   +2 more
openaire   +2 more sources

Development of Spiroligomer–Peptoid Hybrids

The Journal of Organic Chemistry, 2017
Creating functional macromolecules that possess the diversity and functionality of proteins poses an enormous challenge, as this requires large, preorganized macromolecules to facilitate interactions. Peptoids have been shown to interact with proteins, and combinatorial libraries of peptoids have been useful in discovering new ligands for protein ...
Justin D. Northrup   +3 more
openaire   +2 more sources

Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide–peptoid hybrids

Bioorganic & Medicinal Chemistry, 2009
The search for novel, generally applicable and highly efficient delivery tools is a major activity in the biotechnology arena. Using highly optimized microwave based solid-phase chemistry a series of fluorescein-labelled cationic peptoid conjugates were synthesized within 24h and cellular uptake into HeLa, L929 and K562 cells examined via flow ...
Asier, Unciti-Broceta   +4 more
openaire   +2 more sources

Peptoid–Peptide Hybrid Backbone Architectures

ChemBioChem, 2010
AbstractPeptidomimetic oligomers and foldamers have received considerable attention for over a decade, with β‐peptides and the so‐called peptoids (N‐alkylglycine oligomers) representing prominent examples of such architectures. Lately, hybrid or mixed backbones consisting of both α‐ and β‐amino acids (α/β‐peptides) have been investigated in some detail
openaire   +3 more sources

ChemInform Abstract: ′Peptoid′ Design

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
D. C. HORWELL, W. HOWSON, D. C. REES
openaire   +1 more source

Peptoids as tools and sensors

Biopolymers, 2019
AbstractA review of molecular tools and sensors assembled onN‐substituted glycine, or α‐peptoid, oligomers between 2013 and November 2018 with the following sections: (a) Peptoids as crystal growth modifiers, (b) Peptoids as catalysts, (c) Ion and molecule sequestration and transport, (d) Peptoid sensors, (e) Macromolecule recognition, (f) Cellular ...
openaire   +2 more sources

Peptoid residues and beta-turn formation.

Journal of peptide science : an official publication of the European Peptide Society, 2002
A set of terminally protected tripeptoids containing a residue of either N-methylglycine or N-isobutylglycine in position i + 1/i + 2 were synthesized and tested for intramolecularly H-bonded beta-turn formation. By exploiting FT-IR absorption and 1H NMR techniques, their folding tendencies were compared with those of a variety of reference peptides ...
RAINALDI, MARIO   +6 more
openaire   +6 more sources

Cyclic beta-peptoids.

Organic letters, 2008
The first synthesis of functionalized beta-peptoid macrocycles is reported. X-ray crystallographic structure of tetramer 9 reveals a C2-symmetrical derivative with unexpected all-cis-amide bonds and spatial disposition of the appendages toward the two opposite faces of the ring. Quantum calculations suggest that 9 is locked in this layout.
Olivier, Roy   +4 more
openaire   +1 more source

Peptoid Nanomaterials

2020
DANIEL J. MURRAY   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy