Results 81 to 90 of about 834,059 (290)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

DAMPAK PERSEPSI DUKUNGAN ORGANISASI DAN KARATERISTIK PEKERJAAN TERHADAP KNOWLEDGE SHARING: PERAN ORGANIZATIONAL CITIZENSHIP BEHAVIOR SEBAGAI VARABEL MEDIASI

Jurnal Manajemen Universitas Bung Hatta, 2020
Organizational citizenship behavior has been recognized as an important variable for every organization both in academicians and practitioners. The purpose of this study is to investigate the role of organizatinal citizenship behavior as mediator on the ...
Tri Sukma, Fitri Handayani, Sefnedi Sefnedi   +2 more
doaj   +1 more source

Pengaruh Perceived Organizational Support Terhadap Turnover Intention Melalui Kepuasan Kerja Sebagai Variabel Mediator Di Restoran X Surabaya [PDF]

, 2015
Penelitian ini dilakukan untuk menguji analisa pengaruh Perceived Organizational Support terhadap turnover intention dengan kepuasan kerja sebagai variable mediator pada Restoran X.
Bastari, M. V. (Maria), Kartika, E. W. (Endo), Putra, R. G. (Richard)   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Organizational Culture and Perceived Performance: Mediation of Perceived Organizational Support and Moderation of Motivation

Administrative Sciences
This study aimed to investigate the effect of organizational culture on employee-perceived performance and whether this relationship is mediated by perceived organizational support and moderated by employee motivation.
Denise José, Ana Palma-Moreira, Manuel Au-Yong-Oliveira   +2 more
doaj   +1 more source

Organizational Justice and Affective Organizational Commitment: Mediated by Organizational Trust and Perceived Organizational Support

APMBA (Asia Pacific Management and Business Application), 2018
Organizational justice refers to employee perceptions of fairness of treatment by the organization, and their behavioral reactions to this justice. Based on social exchange theory, one consequence of organizational justice is organizational trust, the ...
Ruri Fitria Hayunintyas, Ben Roy Do, Achmad Sudiro, Dodi Wirawan Irawanto   +3 more
doaj   +1 more source

ANALISIS PENGARUH PERCEIVED ORGANIZATIONAL SUPPORT PADA DIMENSI LEARNING ORGANIZATION (Studi pada Karyawan PT. AIR MANCUR, KARANGANYAR) [PDF]

, 2015
Tujuan dari penelitian ini adalah untuk mengetahui efek dari perceived organizational support pada dimensi learning organization. Populasi dalam penelitian ini adalah seluruh karyawan PT. Air Mancur Karanganyar yang berjumlah 378 karyawan.
SUYUDI, SOFYAN IMAM
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source