Results 101 to 110 of about 846,900 (358)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

PENGARUH PERCEIVED ORGANIZATIONAL SUPPORT DAN EMPLOYEE ENGAGEMENT TERHADAP KINERJA KARYAWAN (STUDI PADA PT JASAMARGA PANDAAN MALANG) [PDF]

The purpose of this study is to determine the effect of perceived organizational support and employee engagement on employee performance. The research method used uses quantitative research with an associative approach.
Rahma, Istna
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HUBUNGAN ANTARA PERCEIVED ORGANIZATIONAL SUPPORT (POS) DENGAN MOTIVASI BERPRESTASI PADA ATLET PPLP PROPINSI JAWA BARAT [PDF]

, 2016
Penelitian ini bertujuan untuk mengetahui hubungan antara perceived organizational support (POS) dengan motivasi berprestasi. Perceived organizational support (POS) merupakan persepsi individu mengenai sejauh mana organisasi dapat memberi dukungan yang ...
Fauzy, Hadhy Muhammad
core  

INVESTIGATING THE RELATIONSHIP BETWEEN STRATEGIES FOR COPING WITH NURSES’ STRESS AND PERCEIVED ORGANIZATIONAL SUPPORT IN TEHRAN UNIVERSITY OF MEDICAL SCIENCES HOSPITALS IN 2021, TEHRAN, IRAN [PDF]

, 2022
Tahmineh Naji, Karvan Bekmaz, Afsaneh Sadooghiasl   +2 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pengaruh Perceived Organizational Support terhadap Kinerja Karyawan dengan Employee Engagement sebagai Variabel Intervening (Studi pada Karyawan PT. Pos Indonesia Kota Madiun) [PDF]

, 2017
The aim of this research is to analyze the influence of perceived organizational support (POS) on employee performance mediated by employee engagement. The respondents of this research were 62 employees of PT. Pos Indonesia Madiun City.
Afrianty, T. W. (Tri), Ariarni, N. (Nurmalia)   +1 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Job Stress Ditinjau Dari Perceived Organizational Support Pada Perawat di Rumah Sakit Umum Elpi Al Azis Rantauprapat

Jurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Penelitian ini bertujuan untuk mengeksplorasi hubungan antara Job Stress dan Perceived Organizational Support pada perawat di RSU Elpi Al Azis Rantauprapat.
Sri Hartini, Mulia Risnanda, Ika Kristin Br Manurung, Nicholas Montoya, Rio Fernando Panjaitan   +4 more
doaj   +1 more source

Relationship Between Work-Family Conflict and Perceived Organizational Support Among Nurses of Kurdistan University of Medical Sciences

Caspian Journal of Health Research, 2021
Background: Due to the importance of work-family conflict, it is necessary to find its relationship with organizational variables like perceived organizational support.
Boshra Ebrahimi, Obeidollah Faraji, Bijan Nouri, Sina Valiee   +3 more
doaj  

Hubungan Perceived Organizational Support Terhadap Organizational Citizenship Behavior Melalui Organizational Commitment Pada Beberapa Puskesmas Di DKI Jakarta [PDF]

, 2015
This research refers to a previous study conducted by Nicolas Raineri et al., (2012). This research is about “The Impact of Perceived Organizational Support to Organizational Citizenship Behavior mediated by Organizational Commitment on some health ...
Sari, C. R. (Catalia)
core