Results 71 to 80 of about 111,305 (262)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The effect of perceived organizational support on organizational resilience [PDF]

open access: yes, 2021
Bu araştırmanın amacı algılanan örgütsel desteğin, örgütsel rezilyans üzerindeki etkisini gözlemlemektir. Bu araştırma literatürde algılanan örgütsel desteğin, örgütsel rezilyans üzerindeki etkisini gözlemlemeyi deneyen ilk çalışmadır. Bu araştırmada bir
Murat, Tolga
core  

HUBUNGAN ANTARA PERCEIVED ORGANIZATIONAL SUPPORT DENGAN WORK-LIFE BALANCE PADA KARYAWAN PT. BPR KUSUMA SUMBING DI JAWA TENGAH

open access: yesJurnal Empati, 2019
Penelitian ini bertujuan untuk mengetahui hubungan antara perceived organizational support dengan work-life balance pada karyawan PT. BPR Kusuma Sumbing di Jawa Tengah.
Krisdianti Adinda Puspitasari   +1 more
doaj   +1 more source

DAMPAK PERSEPSI DUKUNGAN ORGANISASI DAN KARATERISTIK PEKERJAAN TERHADAP KNOWLEDGE SHARING: PERAN ORGANIZATIONAL CITIZENSHIP BEHAVIOR SEBAGAI VARABEL MEDIASI

open access: yesJurnal Manajemen Universitas Bung Hatta, 2020
Organizational citizenship behavior has been recognized as an important variable for every organization both in academicians and practitioners. The purpose of this study is to investigate the role of organizatinal citizenship behavior as mediator on the ...
Tri Sukma   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Organizational Commitment: Do Workplace Practices Matter? [PDF]

open access: yes
Using nationally-representative linked employer-employee data for Britain this paper considers whether employers are able to influence the organizational commitment (OC) of their employees through the practices they deploy.
Michael White, Alex Bryson
core  

Perceived organizational support and attitudes toward organizational change : the moderating role of perceived supervisor support [PDF]

open access: yes, 2013
Masteroppgave(MSc) in Master of Science in Leadership and Organizational Psychology - Handelshøyskolen BI, 2013Research on organizational change has identified the crucial role of the employees in whether or not a change initiative is successful.
Blom, Lars, Nordli, Jo Andreas
core  

Exploring the Mechanisms Linking Transformational Leadership, Perceived Organizational Support, Creativity, and Performance in Hospitality: The Mediating Role of Affective Organizational Commitment

open access: yes, 2022
Integrating leadership and creativity theories, this study proposed and examined a model linking transformational leadership, perceived organizational support, affective organizational commitment, creativity, and performance. Structural equation modeling
Wang, Chung-Jen, Chung-Jen Wang
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Do two rights fix a wrong? A study of employee and organizational responses to abusive supervision in New Zealand

open access: yes, 2011
Organizational justice theories suggest that employees who are abused by their supervisor are likely to respond with lower job and personal outcomes. However, an under-explored area has been the influence of support perceptions.
de Fluiter, Alida Jane
core  

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