Results 51 to 60 of about 111,305 (262)

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Drivers of innovative behaviors: The moderator roles of perceived organizational support and psychological empowerment

, 2017
Innovative behaviors are one of the most important factors that affect the competitiv performance of organizations. Although there are numerous studies in the literature which try to determine the antecedents of innovative behaviors. there are still gaps
Yildiz, Bora, Coskun, Serdar Semih, Uzun, Sumeyra   +2 more
core   +1 more source

Gender and the Perceived Equity - Perceived Organizational Support Link in Egypt [PDF]

Eurasian Journal of Business and Economics, 2017
This study aimed at examining the relationships between perceived internal and external salary equities as independent variables, and perceived organizational support (POS) as a dependent variable among Egyptian employees.
Mohamed Hossameldin KHALIFA, Rana ZAKI
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Perceived Organizational Support (POS) With Home Industry Employee Organizational Commitment: Perceived Organizational Support (Pos) dengan Komitmen Organisasi Karyawan Home Industri

, 2023
This study aims to determine the relationship between perceived organizational support (POS) and organizational commitment. This study used a quantitative approach and used a random sampling technique with 150 respondents. The data collection method uses
Amabel, Belsa Azizih Fajar, Paryontri, Ramon Ananda   +1 more
core   +1 more source

The Impact of Organizational Climate and Perceived Organizational Support on Organizational Commitment: The Mediating Role of Job Satisfaction

Indonesian Interdisciplinary Journal of Sharia Economics
This research aims to analyze the influence of organizational climate, perceived organizational support, and job satisfaction on Organizational Commitment. The analysis uses Structural Equation Modeling with the Partial Least Square (PLS) approach.
Minti Hari, Herni Justiana Astuti, Naelati Tubastuvi, Iwan Fakhruddin   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Beyond social exchange: Collectivism’s moderating role in the relationship between perceived organizational support and organizational citizenship behaviour

, 2015
Perceived organizational support plays an important role in the social exchange relationship between the employee and the organization. We propose that individual differences in collectivism affect the extent to which employee–organization relationships ...
van Knippenberg, Daan, van Prooijen, JW, Sleebos, E, van Prooijen, J.W.; id_orcid, Sleebos, E., van Prooijen, J.W., van Knippenberg, Daan; id_orcid, van Knippenberg, D., Sleebos, E.; id_orcid   +8 more
core   +1 more source