Results 51 to 60 of about 804,363 (217)
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Mechanical Engineering Journal, 2016 Output increase of combined cycle power plants is highly expected in order to deal with tight supply-demand situation of electricity and to save fuel consumption.
Shuichi UMEZAWA, Katsuhiko SUGITA
doaj +1 more source
Quiescent Cores and the Efficiency of Turbulence-Accelerated, Magnetically Regulated Star Formation
, 2005 The efficiency of star formation, defined as the ratio of the stellar to total (gas and stellar) mass, is observed to vary from a few percent in regions of dispersed star formation to about a third in cluster-forming cores.
Fumitaka Nakamura +9 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Experimental clean combustor program, phase 3 [PDF]
A two-stage vortex burning and mixing combustor and associated fuel system components were successfully tested at steady state and transient operating conditions.
Fiorentino, A., Greene, W., Roberts, R.
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Turboprop Cargo Aircraft Systems study, phase 1 [PDF]
The effects of advanced propellers (propfan) on aircraft direct operating costs, fuel consumption, and noiseprints were determined. A comparison of three aircraft selected from the results with competitive turbofan aircraft shows that advanced turboprop ...
Hewell, J. G., Jr. +5 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source