Algorithmic performance appraisal intensity in hospitals: implications for professional autonomy and innovative work behavior. [PDF]
Yang Q +5 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Portfolio-Based Performance Appraisal for Doctors: A Case of Paperwork Compliance [PDF]
This paper discusses the findings of research exploring the conduct of portfolio-based performance appraisal within medicine. Portfolios are now used throughout medical school and junior doctor training, in later specialist training, as well as to ...
John Martyn Chamberlain
core
Negotiating reform from within: workforce governance and the expatriate-Saudi interface in the SHSTP era. [PDF]
Abduljawad AA, Alshehri A.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Clinical AI and Precision Medicine: Philosophical Questions About Labels, Disease, and Evidence. [PDF]
Armoundas AA.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Artificial Intelligence-Supported Evidence Synthesis: A Case Study of Smart Infusion Pump Interoperability. [PDF]
Sanchez-Piedra C +4 more
europepmc +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Factors associated with inpatient medical record data quality in hospital settings: a systematic review. [PDF]
Liao P +5 more
europepmc +1 more source

