Results 41 to 50 of about 38,718 (264)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Administrative SciencesPerformance management is critical for aligning human capital with organizational strategy, particularly in the increasingly competitive service sector.
Maria C Tavares, Mariana Vaz
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Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2018 Performance appraisal system is one of the most important determinants for the achievement of goals for human resources management. For that reason, the way and the methods used by organizations to evaluate the performance of their employees are ...
Mustafa GÖRÜN +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Employee’s Perception Towards Organizational Performance Appraisal: A Systematic Literature Review
Management Systems in Production EngineeringPerformance appraisal systems are essential for managing employee performance, yet their success hinges on how employees perceive their fairness, relevance, and impact.
Elabed Salma +3 more
doaj +1 more source
Relationship among EVA, Profitability Ratios and Market value added of listed companies in Tehran Stock Exchange [PDF]
بررسیهای حسابداری و حسابرسی, 2010 Investors tend to know the degree of success of managers in applying their wealth. Due to high sensitivity of investors to the performance of companies wealth is one of the most important objectives of the companies and the performance appraisal systems ...
Mahmood Yahyazadehfar +2 more
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source