Results 91 to 100 of about 35,129,629 (287)

A performance-based generative design framework based on a design grammar for high-rise office towers during early design stage

open access: yesFrontiers of Architectural Research
In the past decade, the construction speed of high-rise office towers worldwide has exhibited explosive growth. The unique morphological characteristics of high-rise office towers result in higher shape factors and relatively larger thermal loads.
Liwei Chen, Ye Zhang, Yue Zheng
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

MFD: Material-based Design Informed by Digital Fabrication

open access: yesMateria Arquitectura, 2016
Recent development of digital fabrication and materialization technologies is enhancing change within design processes. In this work we formulate a new conceptual schema termed Material-Fabrication-Design (MFD).
Rivka Oxman
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A comparative study of modified performance based plastic design methods for seismic design of RC frames: improvement over existing methods

open access: yesScientific Reports
This study introduces a Modified Performance-Based Plastic Design (MPBPD) method to enhance the seismic performance of reinforced concrete special moment-resisting frames.
Rohit Vyas   +10 more
doaj   +1 more source

A Study of Thermal Performance of Contemporary Technology-Rich Educational Spaces [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2013
One of the most dominant features of a classroom space is its high occupancy, which results in high internal heat gain (approximately 5 KW). Furthermore, installation of educational technologies, such as smart boards, projectors and computers in the ...
Sarah Elmasry   +2 more
doaj  

Applying Energy Performance-Based Design in Early Design Stages. A methodological framework for integrating multiple BPS tools [PDF]

open access: yes, 2013
In current architectural practice some important changes are taking place because of the development of numerous Building Performance Simulations (BPS) tools to support design decisions during early phases of the design process.
Ianni, Manuela   +1 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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