Results 101 to 110 of about 2,247,745 (314)
MFD: Material-based Design Informed by Digital Fabrication
Materia Arquitectura, 2016 Recent development of digital fabrication and materialization technologies is enhancing change within design processes. In this work we formulate a new conceptual schema termed Material-Fabrication-Design (MFD).
Rivka Oxman
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Performance management at design actvity level
, 2001 The overriding aim of much of the engineering design research is to improve the performance of the design process, and consequently the product development process. Much has been written within the product development literature on the performance of the
Duffy, A.H.B., O'Donnell, F.J.
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Using design performance measurement as a strategy to improve collaborative design performance
, 2009 This research investigates how to improve collaborative design performance by the implementation of performance measurement. A Design Performance Measurement (DPM) framework is developed to measure collaborative design performance and identify strengths ...
Qin, Sheng-feng +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Performance-Based approach in seismic design of embedded retaining walls
, 2008 The increasing use of the underground spaces and the last seismic events in the urban areas have driven many researchers of different countries to deepen the knowledge on the dynamic behaviour of the structure embedded in the subsoil.
Visone, Ciro
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2002 [Abstract]: A performance-based optimization (PBO) method for optimal topology design of linear elastic continuum structures with mean compliance constraints is presented in this paper.
Steven, Grant P., Liang, Qing Quan
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A Study of Thermal Performance of Contemporary Technology-Rich Educational Spaces [PDF]
Journal of Systemics, Cybernetics and Informatics, 2013 One of the most dominant features of a classroom space is its high occupancy, which results in high internal heat gain (approximately 5 KW). Furthermore, installation of educational technologies, such as smart boards, projectors and computers in the ...
Sarah Elmasry +2 more
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