Results 61 to 70 of about 70,536 (266)

Zootechnical Performances of Goats in Niger: Comparative Study of the Maradi Russet Goat with the Black-Coat Goat in Maradi Area

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2002
The main objective of this study was not only to contribute to the knowledge of the Maradi russet goat, but also to compare some of its parameters (reproduction, adult weight, measurements, growth) with those of the black goat. Retrospective oral surveys
H. Marichatou, L. Mamane, M. Banoin, G. Baril   +3 more
doaj   +1 more source

Effet de l’alimentation et des facteurs d’élevage sur les performances de reproduction de chevrettes Alpines

INRAE Productions Animales, 1998
Nous avons étudié, au cours de quatre essais sur des chevrettes Alpine (n=158), les facteurs de variation de la réussite à l’insémination artificielle (IA) réalisée à un âge moyen de 8 mois. Après une mise en lot sur des critères zootechniques, les régimes expérimentaux ont été appliqués depuis 25 jours avant et jusqu’à 21 jours après l’IA. En moyenne,
Bocquier, F., Leboeuf, Bernard, Rouel, J., Chilliard, Yves   +3 more
openaire   +4 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Research priorities in trans health: a Delphi-study

Frontiers in Public Health
PurposeProgress has been made in understanding trans health needs, but research priorities are often set by policy or healthcare professionals without trans input, which may not reflect public needs.
Lucie Jurek, Lucie Jurek, Marie De la Chenelière, Marion Lapoirie, Paul Neuville, Paul Neuville   +5 more
doaj   +1 more source

Productivity of the Borgu breed at the Okpara breeding farm in Benin

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2000
The productivity of the Borgu breed was studied from 1994 to 1997 at the Okpara Breeding Farm in Benin with 2577 animals on average per year. The breeding mode was of the semi-improved type.
A.K. I. Youssao, A. Ahissou, Z. Touré, P. L. Leroy   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Evaluation de la productivité et de la mortalité de la poule locale sur le plateau du Sankaran, Faranah, Guinée, en 1993-1994

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1997
Cet article traite de la productivité et de la mortalité de la poule de race locale en milieu villageois (plateau du Sankaran). La productivité de cette poule était très modeste, caractérisée par le nombre d'œufs par couvée (10,05 + ou - 0,15) et le ...
M. Mourad, A.S. Bah, G. Gbanamou
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source