Results 81 to 90 of about 73,546 (303)

Productivity of the Borgu breed at the Okpara breeding farm in Benin

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2000
The productivity of the Borgu breed was studied from 1994 to 1997 at the Okpara Breeding Farm in Benin with 2577 animals on average per year. The breeding mode was of the semi-improved type.
A.K. I. Youssao   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Evaluation de la productivité et de la mortalité de la poule locale sur le plateau du Sankaran, Faranah, Guinée, en 1993-1994

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1997
Cet article traite de la productivité et de la mortalité de la poule de race locale en milieu villageois (plateau du Sankaran). La productivité de cette poule était très modeste, caractérisée par le nombre d'œufs par couvée (10,05 + ou - 0,15) et le ...
M. Mourad, A.S. Bah, G. Gbanamou
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Superar no movimento: etnografia de performances de Pirráias em Recife e mais além [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Antrolopologia Social.Esta etnografia é um estudo de performances de crianças e adolescentes nas ruas e praças de dois bairros
Silva, Rita de Cácia Oenning da
core  

Amélioration des performances de reproduction et bien être en élevage

open access: yes, 2018
National audienceThis article reviews the relationship between farm animal welfare and the reproductive performance of cattle. The improvement of the welfare of cattle responds to strong societal expectations, but also provides a technical advantage for ...
Ledoux, Dorothee   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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