Results 101 to 110 of about 65,936,322 (300)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1997 Une typologie des élevages de cerfs a été réalisée grâce à la méthode graphique de Bertin. Quatre grands types d'élevage qui se différenciaient essentiellement selon la superficie des pâturages, le chargement moyen et l'intensification des pratiques d ...
Sébastien Le Bel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1981 Après avoir brièvement décrit le fonctionnement traditionnel des parcs villageois du Nord-ivoirien et la vocation de cet élevage bovin, les auteurs présentent les grandes lignes du programme de recherches mis en place dans ce cadre, en vue de la ...
Jean-Paul Poivey +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A review of maturation and reproduction in closed thelycum penaeids [PDF]
, 1985 Commercially important penaeids of the closed thelycum group belong to five subgenera of the genus Penaeus — Penaeus, Fenneropenaeus, Marsupenaeus and Melicertus that are almost exclusively Indo-West Pacific and Farfantepenaeus that is predominantly ...
Jurgenne H. Primavera +1 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996 Trois lots de 14 brebis Djallonké ont été comparés : l'un (lot E) avec un traitement antiparasitaire à la mise bas avec de l'Ivomec® ou du Valbazen® et de l'Amprol®, l'autre (lot T2) avec trois traitements antiparasitaires classiques avec les mêmes ...
Sylvie Hounzangbe-Adote, Christian Meyer
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Perfil das usuárias do sistema intrauterino liberador de levonorgestrel (SIU-LNG) e aceitabilidade do método em Florianópolis (SC) [PDF]
, 2004 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Moreira, Juliana
core