Results 111 to 120 of about 65,936,322 (300)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Métodos aplicáveis a medição e avaliação da performance logística como bases para o gerenciamento de mudanças [PDF]

open access: yes, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.As definições sobre performance empresarial e performance logística são ainda controvertidas dentro do meio acadêmico
Souza, Antonio Goes Camelier de
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

(Un)natural Bodies: Reproduction, Disability, Queerness [PDF]

open access: yes, 2011
This dissertation arises from an interdisciplinary attention to the categories of embodiment, otherness, and the "abnormal." In deconstructing a "normal" versus "abnormal" binary, I focus specifically on establishing intersections between disabled and/
Narduzzi, Dilia
core  

Examen de l’aptitude à la reproduction chez le bélier et le bouc

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2018
L’examen de l’aptitude à la reproduction (EAR) du mâle est une composante importante de l’élevage des petits ruminants. L’EAR est mieux réalisée 2 mois avant la saison de reproduction.
A. TIBARY, R. BOUKHLIQ, K. EL ALLALI
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Le système kisspeptine : Au coeur du contrôle de la reproduction

open access: yes, 2015
National audienceDepuis la découverte de son importance en physiologie de la reproduction, le système composé par le neuropeptide kisspeptine et son récepteur (KISS1R) a fait l’objet d’une intense activité de recherche.
Beltramo, Massimiliano   +1 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Performance

open access: yes
Representing the output of the research project "Performance: Conservation, Materiality, Knowledge," this volume brings together diverse voices, methods, and formats in the discussion and practice of performance conservation.

core   +1 more source

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