Results 131 to 140 of about 1,595,621 (298)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Management of Reproduction in Dairy Herds with Natural Service or Timed Artificial Insemination

EDIS, 2011
Both natural service and artificial insemination programs can work for managing reproduction on dairy farms. This 3-page fact sheet provides comparison of reproductive performance and economic considerations. Written by Fábio S.
Fábio S. Lima, Albert De Vries, Carlos A. Risco, José E. P. Santos   +3 more
doaj   +1 more source

Phenotypically Plastic Responses to Predation Risk Are Temperature Dependent [PDF]

, 2019
Predicting how organisms respond to climate change requires that we understand the temperature dependence of fitness in relevant ecological contexts (e.g., with or without predation risk).
Cressler, Clayton E., DeLong, John, Luhring, Thomas M., Vavra, Janna M.   +3 more
core   +1 more source

Intérêt d'un traitement antiparasitaire contre les strongles et les coccidies à l'agnelage de la brebis Djallonké

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
Trois lots de 14 brebis Djallonké ont été comparés : l'un (lot E) avec un traitement antiparasitaire à la mise bas avec de l'Ivomec® ou du Valbazen® et de l'Amprol®, l'autre (lot T2) avec trois traitements antiparasitaires classiques avec les mêmes ...
Sylvie Hounzangbe-Adote, Christian Meyer
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Le mouton Djalonké de Côte-Ivoire en milieu villageois, comportement et alimentation

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1976
Le comportement du mouton à poil ras des zones tropicales humides est fort peu connu. Son élevage se heurte à de nombreuses difficultés. En plus des maladies diverses, il semble bien que la dégénérescence, les saillies et gestations précoces, la ...
D. Rombaut, Guy Van Vlaenderen
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Finalités et aspects méthodologiques d'un système informatisé de suivi individuel des animaux dans les élevages bovins villageois du Nord de la Côte d'Ivoire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1981
Après avoir brièvement décrit le fonctionnement traditionnel des parcs villageois du Nord-ivoirien et la vocation de cet élevage bovin, les auteurs présentent les grandes lignes du programme de recherches mis en place dans ce cadre, en vue de la ...
Jean-Paul Poivey, J.L. Seitz, Etienne Landais   +2 more
doaj   +1 more source

Animal breeding in organic farming:Discussion paper [PDF]

, 2001
It is uncertain whether animals which have been bred for conventional production are capable of optimum performance in organic conditions. In conventional agriculture there is a movement towards maximum control of production conditions in order to ...
Baars, Nauta, Groen, Ab, Nauta, Wytze, Roep, Dirk, Veerkamp, Roel   +4 more
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