Results 141 to 150 of about 1,595,621 (298)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Typologie des élevages de cerfs en Nouvelle-Calédonie et impact d'un suivi des performances d'abattage

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1997
Une typologie des élevages de cerfs a été réalisée grâce à la méthode graphique de Bertin. Quatre grands types d'élevage qui se différenciaient essentiellement selon la superficie des pâturages, le chargement moyen et l'intensification des pratiques d ...
Sébastien Le Bel   +2 more
doaj   +1 more source

Has Ambisonics come of age? [PDF]

open access: yes, 2008
Ambisonics was developed in the 1970’s as a flexible, psycho-acoustically aware system1. Developed at the same time as Quadraphonics2, Ambisonics is an often mis-understood system that was far ahead of it’s time.
Wiggins, Bruce
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Examen de l’aptitude à la reproduction chez le bélier et le bouc

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2018
L’examen de l’aptitude à la reproduction (EAR) du mâle est une composante importante de l’élevage des petits ruminants. L’EAR est mieux réalisée 2 mois avant la saison de reproduction.
A. TIBARY, R. BOUKHLIQ, K. EL ALLALI
doaj  

One-pass adaptive universal vector quantization [PDF]

open access: yes, 1994
The authors introduce a one-pass adaptive universal quantization technique for real, bounded alphabet, stationary sources. The algorithm is set on line without any prior knowledge of the statistics of the sources which it might encounter and ...
Chou, P. A., Effros, M., Gray, R. M.
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy