Results 91 to 100 of about 1,547,128 (294)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Enhancement of thrust reverser cascade performance using aerodynamic and structural integration [PDF]

, 2004
This paper focuses on the design of a cascade within a cold stream thrust reverser during the early, conceptual stage of the product development process.
Armstrong, Cecil, Butterfield, Joseph, Bénard, Emmanuel, Cooper, Richard K., Monaghan, D., Price, Mark, Raghunathan, Srinivasan, Yao, H.   +7 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

ENHANCE PERFORMANCE. [PDF]

Chemical & Engineering News Archive, 1998
  +8 more sources

Immediate effects of ultrasound therapy on pain and plantar pressure in individuals with subacute ankle sprains: a randomized controlled trial

Physiotherapy Quarterly
Introduction Despite the fact that ultrasound (US) therapy is not advised for acute ankle sprains, its therapeutic effects may be beneficial for other stages of ankle sprains, such as a subacute ankle sprain.
Thongchai Suksri, Chitanongk Gaogasigam, Sujitra Boonyong   +2 more
doaj   +1 more source

The effect of carnosine or β-alanine supplementation on markers of glycaemic control and insulin resistance in human and animal studies: a protocol for a systematic review and meta-analysis

Systematic Reviews, 2020
Background Diabetes is a major public health issue and there is a need to develop low-cost, novel interventions to prevent or reduce disease progression. Growing evidence shows that supplementation with carnosine, or its rate-limiting precursor β-alanine,
Joseph J. Matthews, Eimear Dolan, Paul A. Swinton, Livia Santos, Guilherme G. Artioli, Mark D. Turner, Kirsty J. Elliott-Sale, Craig Sale   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Chronological age and biological maturity are separately positively associated with inhibitory control and working memory in boys and girls

Frontiers in Cognition
Executive function is typically considered from a chronological age perspective, despite the influence of biological maturity on executive function development.
Luke M. Gilbert, Ryan A. Williams, John G. Morris, Anna Dunn, Ruth Boat, Karah J. Dring, Mary E. Nevill, Simon B. Cooper   +7 more
doaj   +1 more source

Photonic quasi-crystal LEDs: design, modelling, and optimisation

, 2007
In this paper we investigate improvement in performance attainable by etching Photonic Crystals and Photonic Quasi-Crystals into the top emitting surface of LEDs.
Charlton, M.D.B., Lee, T., Zoorob, M.E.
core   +1 more source