Results 71 to 80 of about 9,772,737 (279)

Performance-enhancing substances: What athletes are using

Cleveland Clinic Journal of Medicine, 2001
Use of performance-enhancing substances is widespread among competitive athletes, whether professional or amateur, adolescent or adult. Some of these substances are legal and beneficial, but others are illegal or have adverse or unproven effects. This article describes the action and effects of these substances, their legality, and their potential for ...
openaire   +2 more sources

Pre-Workout Supplements and Their Effects on Cardiovascular Health: An Integrative Review

Journal of Cardiovascular Development and Disease
Introduction: Dietary supplements have become a popular aid for improving training performance. Pre-workout supplements contain a mixture of ingredients used to boost physical performance, with some components having been associated with the promotion of
Yanesko Fernandes Bella, Samantha Rodrigues Silva Cupido, Pedro Augusto Querido Inacio, Marcelo Luiz Peixoto Sobral, Rodolfo P. Vieira   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Wrestler's Heart: Cardiac Remodeling in World Wrestling Entertainment Athletes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence on cardiac adaptation in elite wrestlers remains limited. This study assessed electrical and structural cardiac remodeling in elite wrestlers, with particular focus on sex‐specific differences.
Lorenzo‐Lupo Dei, Nithiwat Tangchompoo, Tiziana Cristina Minopoli, Michael Papadakis, Sanjay Sharma, Gherardo Finocchiaro   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Performance-enhancing substances in sport: An ethical study

, 1990
Questions concerning whether current policies restricting the use of performance enhancing substances in sport are morally or ethically justified have not received the attention they deserve from philosophers of sport.
Gardner, Roger William
core   +1 more source

A Scientometric Insight into 70 Years of Research in Performance-Enhancing Substances in Sports

Emerging Trends in Drugs, Addictions, and Health
Introduction: The use of performance-enhancing substances is extremely high among athletes. Besides compromising the spirit of fair sport competition, performance-enhancing substances also pose a serious threat to athletes’ health.
A. Carollo, O. Rabin, O. Corazza, G. Esposito   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Methylphenidate as a cognitive enhancer in healthy young people

Dementia & Neuropsychologia
The so-called cognitive enhancers have been widely and increasingly used by healthy individuals who seek improvements in cognitive performance despite having no pathologies.
Silmara Batistela, Orlando Francisco Amodeo Bueno, Leonardo José Vaz, José Carlos Fernandes Galduróz   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source