Results 91 to 100 of about 9,772,737 (279)
Protective factors of performance-enhancing substances use in a sample of Portuguese gym-goers [PDF]
This project was supported by national funds through FCT - Fundação para a Ciência e Tecnologia: FCT/MCTES (UIDB/05608/2020 and UIDP/05608/2020).Background: Nowadays, the increased Performance Enhancing-Substance (PES) use in fitness centers is seen as a
Tavares, Ana Sofia +4 more
core
, 2013 The Gateway Hypothesis was examined with respect to appearance- and performance-enhancing substance use. Various sociocultural influences on substance use were also included in the analysis to determine whether prior substance use predicts current use ...
Crowther, J. H. +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
An educational placebo effect intervention reduces the likelihood of athletes using performance enhancing drugs [PDF]
, 2018 Background Recent research has reported that placebo effects can significantly improve sport performance. However, while research has generated knowledge about placebo effects on sport performance, there is limited research devoted to how this can ...
Beedie, C. +3 more
core
Adverse events and safety concerns among university students who misused stimulants to increase academic performance [PDF]
Einstein (São Paulo)Objective: To evaluate psychostimulant drug use among academics in the health area of a higher education institution in Minas Gerais, Brazil. Methods: We conducted an online cross-sectional study of 389 university students from various health-related ...
Joyce Emanuelle Moreira +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Are doping substances imported into Switzerland mainly to increase athletic performance
, 2016 Background: Doping substances are those thought to increase athletic performance, enhance image, or overcome the effects of ageing. This study aims to evaluate the profiles of people and the reasons for importing substances appearing on the World Anti ...
Lentillon-Kaestner, Vanessa +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source