Results 151 to 160 of about 3,955,631 (310)

A comparison of sensor-based lower extremity reaction times, walking speeds, functional performance, and activity fear in older adults with a history of falls: a cross-sectional study. [PDF]

BMC Geriatr
Çekok FK, Anaforoğlu B.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Improved Business Performance by Analysing History

Measurement + Control, 2002
Iain Crosley
doaj   +1 more source

Advanced artificial intelligence vs simpler models for 1-year death prediction among patients receiving hemodialysis. [PDF]

JAMIA Open
K K, Flythe JE, Pun PH, Winkelmayer WC, Carlson D.   +4 more
europepmc   +1 more source

Data-Space Inversion with Ensemble Smoother

, 2019
Reservoir engineers use large-scale numerical models to predict the production performance in oil and gas fields. However, these models are constructed based on scarce and often inaccurate data, making their predictions highly uncertain.
Emerick, Alexandre A., Lima, Mateus M., Ortiz, Carlos E. P.   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Safety-First Framework for AI-Enabled Anamnesis in Head and Neck Surgery: Evidence Synthesis from a Narrative Review. [PDF]

J Clin Med
Vaira LA, Qadeer H, Lechien JR, Maniaci A, Maglitto F, Troise S, Chiesa-Estomba CM, Consorti G, Cirignaco G, Iannella G, Navarro-Cuéllar C, Salzano G, Soro GM, Boscolo-Rizzo P, Vellone V, De Riu G.   +15 more
europepmc   +1 more source

Growth, Colonization, and Institutional Development: In and Out of Africa [PDF]

This essay investigates the determinants of the growth performance of Africa. I start by illustrating a broader research agenda which accounts not only for basic economic and demographic factors, but also for the role of history and institutional ...
Bertocchi, Graziella
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source