Results 181 to 190 of about 18,439,231 (382)

Handbook of recommended practices for the determination of liquid monopropellant rocket engine performance [PDF]

The design, installation, and operation of systems to be used for directly measuring quantities of fundamental importance to the determination of monopropellant thruster performance is described. Areas covered include: (1) force and impulse measurement; (
Baerwald, R. K., Bjorklund, R. A., Rogero, R. S.   +2 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The Ambiguous Impact of Performance Measurement on Service Quality. [PDF]

Front Rehabil Sci, 2022
Tøssebro J, Mjøen OM, Bruteig R.
europepmc   +1 more source

Physical performance measures

, 2013
Geschikte testen nodig om bij ouderen met cognitieve problemen :- effect behandeling meten (groepen/individu)- functionele status- screening/diagnostiek. Deze presentatie bespreekt de evidence based (valide en betrouwbare) meetinstrumenten.
openaire  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Performance measurement of nonhomogeneous Hong Kong hospitals using directional distance functions. [PDF]

Health Care Manag Sci, 2023
Lin S, Rouse P, Wang YM, Lin L, Zheng ZQ.   +4 more
europepmc   +1 more source

PERFORMANCE AND ENERGY-TRANSFER MEASUREMENTS ON CYLINDRICAL CESIUM THERMIONIC CONVERTERS

, 1963
John W. Holland
openalex   +1 more source

Performance measurement in a university computing facility [PDF]

, 1972
Maggie Draper, Toby J. Teorey
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Performance Measurement for Opioid Use Disorder Medication Treatment and Care Retention. [PDF]

Am J Psychiatry, 2023
Williams AR, Mauro CM, Feng T, Wilson A, Cruz A, Olfson M, Crystal S, Samples H, Chiodo L.   +8 more
europepmc   +1 more source