Results 111 to 120 of about 10,311,340 (298)

Effects of home-based slow-paced breathing on functional performance in middle-aged women: A randomized controlled trial study

Experimental Gerontology
As individuals age, functional performance declines, particularly affecting mobility, strength, and postural balance, with middle-aged women experiencing earlier and more pronounced impairments due to menopausal transition.
Karama Masmoudi, Fatma Chaari, Haithem Rebai, Sonia Sahli   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Pumping up your predictive power for cognitive state detection with the proper GAINS

NeuroImage
Detecting cognitive states and impairments through EEG signals is crucial for applications in aviation and medicine and has broad applications in the field of human–machine interaction.
Victoria Ribeiro Rodrigues, Jeremy R. Prieto, Szilard L. Beres, Chad Stephens, Christopher Myers, Nicholas J. Napoli   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Examining the Effects of Altitude on Workload Demands in Professional Basketball Players during the Preseason Phase

Sensors
Basketball involves frequent high-intensity movements requiring optimal aerobic power. Altitude training can enhance physiological adaptations, but research examining its effects in basketball is limited.
Sergio J. Ibáñez, Carlos D. Gómez-Carmona, Sergio González-Espinosa, David Mancha-Triguero   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Scenario Optimization: The Performance-Risk Tradeoff

, 2018
Scenario optimization considers decisions made on the grounds of past experience. A scenario decision is characterized by two fundamental elements: one is the performance the decision is expected to achieve and the other is the risk that this expected ...
Garatti, Simone
core   +1 more source

Vertical Force–Velocity Profiling in Soccer: A Systematic Review of Evidence, Assumptions, and Limitations

Journal of Functional Morphology and Kinesiology
Background: This systematic review critically examined how vertical force–velocity profiling has been used and interpreted in soccer research, with particular attention to methodological limitations and practical constraints.
Khairi Salim, El Mouahid Khalid, Chmura Paweł, Rfaki Abderrazak   +3 more
doaj   +1 more source