Results 101 to 110 of about 2,300,519 (313)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Impact of Software Quality on Organizational Performance
ArraySoftware has emerged as a critical strategic asset that drives organizational success and competitive advantage. In today’s software-centric economy, businesses manage their software resources to enhance organizational performance effectively. However, low-quality software systems can significantly hinder this goal.
Ahmad Nabot, Ahmad Al-Qerem
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Parallel enrollments: associations between university student life and performance
Cogent EducationAustria’s university system has no tuition fees and allows students to enroll in an unlimited number of programs simultaneously, regulated via legal measures to ensure fast and efficient studying and especially challenging those with more than one ...
Alexander Karl Ferdinand Loder +2 more
doaj +1 more source
Quality of service attributes based hybrid decision-making framework for ranking cloud service providers under Fermatean fuzzy environment [PDF]
Yugoslav Journal of Operations ResearchCloud Computing has gained substantial popularity due to its ability to offer diverse and dependable computing services suited to clients demands. Given the rapid expansion of this technology, an increasing number of IT service providers are competing to
Al-Mashhadani Athraa Kamel +2 more
doaj +1 more source
Quality management system and construction performance
, 2011 This paper discusses the level of effectiveness of quality principles and quality management system implementation and the relationship with performance of ISO9000 certified Indonesian contractors.
V. Coffey +5 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied SciencesIn contemporary sports science, the integration of wearable inertial measurement units (IMUs) has revolutionized athlete performance monitoring, offering insights into training load management and injury risk mitigation. The acute:chronic workload ratio (
Salvatore Pinelli +3 more
doaj +1 more source
Children's health and safety: an analysis of Quality Area 2 of the National Quality Standard [PDF]
, 2016 ACECQA has published the second in its series of occasional papers, analysing one of the most challenging quality areas - Children’s Health and Safety.
Australian Children’s Education and Care Quality Authority
core
Hard quality management and performance: the moderating role of soft quality management [PDF]
, 2017 The main aim of this study is to examine the moderating role of soft quality management practices (management commitment, customer focus, employee involvement, training and education, reward and recognition and supplier relationship) between hard quality
Tarí, Juan José +1 more
core +1 more source