Perspectives on Medical EducationIntroduction: For future doctors, learning compassion skills is heavily dependent on female and male faculty’s role modelling in practice. As such, more insight into the relationships between faculty’s compassionate behavior, faculty gender and role ...
Rosa Bogerd +4 more
doaj +1 more source
Do we measure what we get? [PDF]
, 2008 Performance measures shall enhance the performance of companies by directing the attention of decision makers towards the achievement of organizational goals.
Kunz, Jennifer
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
南方能源建设[Objective] Large-diameter monopile foundations are widely used in marine engineering in China and are typically installed through penetration. Due to the impact of the pile hammer, the pile body experiences continuous impact loads during the driving ...
Tao CHEN +4 more
doaj +1 more source
Effect of academic stress, educational environment on academic performance & quality of life of medical & dental students; gauging the understanding of health care professionals on factors affecting stress: A mixed method study. [PDF]
PLoS One, 2023 Wahid MH +7 more
europepmc +1 more source
Managing quality in organizations through performance measurement [PDF]
The performance measurement of an organization’s processes offers important information regarding to what extend the settled objectives have been fulfilled, and also its progress.
Carmen PANTEA +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ninety-Day Emergency Department Rebound Following Adult Tonsillectomy: A Retrospective Cohort Study
Journal of Otolaryngology - Head and Neck SurgeryImportance Post-tonsillectomy complications often present in emergency departments (EDs). Reducing postoperative ED visits is one strategy to relieve the strain on healthcare systems and patients.
Kalpesh Hathi MD +4 more
doaj +1 more source