DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
QUALITY MANAGEMENT AND PERFORMANCE IMPROVEMENT IN PUBLIC INSTITUTIONS BY BENCHMARKING APPLICATION [PDF]
Within the performed survey, the authors analyze the benchmarking definitive elements, identify the main categories of the approach referring to benchmarking, and underline the positive aspects and the critics in connection with it.
Marilena CIOBANASU +2 more
core
Risk Management and Healthcare PolicyAmmar K Alomran,1 Amal AlOdaini,2 Maher S Alqurashi,3 Reem M Althwanay,4 Razan Abdullah Alshehri,4 Randa T Alsweed,4 Razan Essam Alharbi,4 Buthainah A Algarni,4 Reem Alturki,5 Arwa Alumran6 1Department of Orthopedic, College of Medicine, Imam Abdulrahman
Alomran AK +9 more
doaj
Past social support influences pre-performance self-confidence and performance quality among student musicians. [PDF]
Front PsycholYoshie M, Morijiri Y.
europepmc +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Performance Quality Rating Scale for Somatosensation After Stroke Version 3: Reliability, Feasibility. [PDF]
OTJR (Thorofare N J)Wanklyn T, Webster KE, Carey LM.
europepmc +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
A Pilot Study on the Effects of Exercise Training on Cardiorespiratory Performance, Quality of Life, and Immunologic Variables in Long COVID. [PDF]
J Clin MedAbbasi A +11 more
europepmc +1 more source