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Perfringolysin O pore-forming complexes are predominantly integral multiples of six subunits

Abstract Perfringolysin O is a well-studied bacterial cytolysin that forms large oligomeric pores with a wide range of sizes on membranes via a prepore intermediate. Here we examined the sizes of both PFO prepore and pore complexes electrophoretically using a multi-stack-gradient gel and found that, unexpectedly, there are only at most ...
Meijun Liu   +7 more
openaire   +1 more source

Perfringolysin O and related cholesterol-dependent cytolysins

2015
Kristin R. Wade   +2 more
openaire   +1 more source

Repurposing rabeprazole sodium as an anti-Clostridium perfringensdrug by inhibiting perfringolysin O

Journal of Applied Microbiology, 2023
Xuming Deng, Haihua Feng, Quanshun Li
exaly  

Membrane disorganization induced by perfringolysin O (theta-toxin) of Clostridium perfringens — effect of toxin binding and self-assembly on liposomes

Biochimica Et Biophysica Acta - Biomembranes, 1993
Yoshiko Ohno-Iwashita   +2 more
exaly  

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