Results 111 to 120 of about 907,151 (342)

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

open access: yesAdvanced Healthcare Materials, EarlyView.
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz   +8 more
wiley   +1 more source

Thyroid Hormone as a Method of Reducing Damage to Donor Hearts after Circulatory Arrest [PDF]

open access: yes, 2017
There is a chronic lack of donor hearts to meet the need for heart transplant both in the US and worldwide. Further, the use of available hearts is limited by the short period between collection and implantation during which the heart can be safely ...
Adams, William P.
core   +1 more source

Static and dynamic assessment of myocardial perfusion by computed tomography [PDF]

open access: bronze, 2016
Ibrahim Danad   +3 more
openalex   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter   +5 more
wiley   +1 more source

Whole-mount imaging of the mouse hindlimb vasculature using the lipophilic carbocyanine dye DiI.

open access: yesBioTechniques, 2012
The availability of transgenic disease backgrounds and the accessibility of molecular research reagents have contributed to make the mouse ischemic hindlimb the model of choice for many studies of angiogenesis, and to investigate new treatments for ...
Jeffrey Boden   +6 more
doaj   +1 more source

Cerebral Perfusion is Associated With White Matter Hyperintensities in Older Adults With Heart Failure [PDF]

open access: bronze, 2013
Michael L. Alosco   +13 more
openalex   +1 more source

Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute   +5 more
wiley   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li   +8 more
wiley   +1 more source

Diferencia de la presión arterial media antes y durante un bypass cardiopulmonar: ¿cuál debe ser la presión de perfusión media ideal?

open access: yesCirugía y Cirujanos
Objetivo: La diferencia de la presión arterial media (PAM) antes del bypass cardiopulmonar y la presión de perfusión media (PPM) durante el bypass cardiopulmonar se considera un factor predictivo importante de insuficiencia renal aguda (IRA).
Bişar Amaç   +3 more
doaj   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

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