Results 111 to 120 of about 787,249 (370)
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Advanced Functional Materials, EarlyView.Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi +6 more
wiley +1 more source
Frontiers in Bioscience, 2012 Isolated lung perfusion (ILP) has been historically used as a method to study basic lung physiologic concepts using animal models. More recently, ILP has been applied in lung transplantation and thoracic oncology. In lung transplantation, ILP has been used to assess physiological integrity of donor lungs after the organ is removed from the donor.
Shaf Keshavjee, Marcelo Cypel
openaire +3 more sources
Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels
Advanced Functional Materials, EarlyView.A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco +12 more
wiley +1 more source
Ensemble Kalman Filters for reliability estimation in perfusion inference [PDF]
arXiv, 2018 We consider the solution of inverse problems in dynamic contrast-enhanced imaging by means of Ensemble Kalman Filters. Our quantity of interest is blood perfusion, i.e. blood flow rates in tissue. While existing approaches to compute blood perfusion parameters for given time series of radiological measurements mainly rely on deterministic ...
arxiv
Oxidized Carbon Nanoparticles Enhance Cellular Energetics With Application to Injured Brain
Advanced Healthcare Materials, Volume 14, Issue 8, March 25, 2025.Oxidized carbon nanozymes (OCNs) that catalyze the dismutation of superoxide radical and oxidation of reduced nicotinamide adenine dinucleotide (NADH) to NAD+ promote glycolytic and mitochondrial energy metabolism under impaired conditions observed in traumatic brain injury with hemorrhage.
Karthik Mouli +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino +9 more
wiley +1 more source
The Cardiothoracic SurgeonBackground The development of the cardiopulmonary bypass machine for extracorporeal circulation by Dr. John Gibbon marked a significant milestone in the advancement of medical technology.
Trasha Shetty +2 more
doaj +1 more source
The Journal of ExtraCorporeal TechnologyBackground: Patients receiving mechanical circulatory support (MCS) frequently require renal replacement therapy (RRT). Examining risk factors for requiring RRT in patients receiving MCS may allow improved understanding of these comorbidities and enhance
Gore Kelsey +8 more
doaj +1 more source
Normothermic Perfusion is Superior to Cold Perfusion in Porcine Ex Situ Lung Perfusion
Transplantation ProceedingsCold ex situ lung perfusion (ESLP) has demonstrated improved preservation in small animal ESLP compared to normothermic ESLP and cold static preservation. We hypothesized that cold negative pressure ventilation (NPV)-ESLP would improve graft function in a porcine transplantation model.Four perfusate temperatures were examined with 12 hours NPV-ESLP in ...
Keir Forgie +11 more
openaire +2 more sources