Results 51 to 60 of about 787,249 (370)

Brain Tissues Segmentation on MR Perfusion Images Using CUSUM Filter for Boundary Pixels [PDF]

International Journal of Computing (2019), V. 18, N 2., P. 127-134, 2019
The fully automated and relatively accurate method of brain tissues segmentation on T2-weighted magnetic resonance perfusion images is proposed. Segmentation with this method provides a possibility to obtain perfusion region of interest on images with abnormal brain anatomy that is very important for perfusion analysis.
arxiv   +1 more source

Adapting and applying student-centered learning in a perfusion clinical rotation

The Journal of ExtraCorporeal Technology
While the process of teaching student perfusionists has been in development since the 1950s, the publication of the processes to improve perfusion clinical education has been largely lacking.
Neal James R., Blau Caitlin, Colby Clint
doaj   +1 more source

Hypothermic liver perfusion [PDF]

Current Opinion in Organ Transplantation, 2017
The review describes recent developments in hypothermic machine liver perfusion with a special focus on underlying protective mechanisms, and the role of this perfusion technique in high-risk donor-recipient combinations.To maximize the number of transplantable donor livers, several centres are exploring new machine preservation techniques.
Schlegel, Andrea, Muller, Xavier, Dutkowski, Philipp   +2 more
openaire   +3 more sources

Acute Effect of Repeated Sprint Exercise With Blood Flow Restriction During Rest Periods on Muscle Oxygenation

Frontiers in Physiology, 2021
PurposeThis study aimed to examine the effect of applying BFR during rest periods of repeated cycling sprints on muscle oxygenation.MethodsSeven active males performed 5 × 10-s maximal pedaling efforts with 40-s passive rest, with or without BFR ...
Chihiro Kojima, Keiichi Yamaguchi, Hiroto Ito, Nobukazu Kasai, Olivier Girard, Kazushige Goto   +5 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Non-invasive assessment of acute heart failure by Stevenson classification: Does echocardiographic examination recognize different phenotypes?

Frontiers in Cardiovascular Medicine, 2022
BackgroundAcute heart failure (AHF) presentation is universally classified in relation to the presence or absence of congestion and the peripheral perfusion condition according to the Stevenson diagram.
Alberto Palazzuoli, Gaetano Ruocco, Serafina Valente, Andrea Stefanini, Erberto Carluccio, Giuseppe Ambrosio   +5 more
doaj   +1 more source

Pretransplant sequential hypo‐ and normothermic machine perfusion of suboptimal livers donated after circulatory death using a hemoglobin‐based oxygen carrier perfusion solution

American Journal of Transplantation, 2019
Ex situ dual hypothermic oxygenated machine perfusion (DHOPE) and normothermic machine perfusion (NMP) of donor livers may have a complementary effect when applied sequentially.
Y. de Vries, A. Matton, M. Nijsten, M. J. Werner, A. P. van den Berg, M. D. de Boer, C. Buis, M. Fujiyoshi, R. D. de Kleine, O. B. van Leeuwen, P. Meyer, M. C. van den Heuvel, V. D. de Meijer, R. Porte   +13 more
semanticscholar   +1 more source

Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells

FEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki, Kiichi Hirota, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Mikio Hayashi   +5 more
wiley   +1 more source