Measurements of peri-prostatic adipose tissue by MRI predict bone metastasis in patients with newly diagnosed prostate cancer [PDF]
ObjectivesTo investigate the role of MRI measurements of peri-prostatic adipose tissue (PPAT) in predicting bone metastasis (BM) in patients with newly diagnosed prostate cancer (PCa).MethodsWe performed a retrospective study on 156 patients newly ...
Bo-Hao Liu +11 more
doaj +9 more sources
Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue [PDF]
Background The causative role of the pro-inflammatory cytokine IL-6 in prostate cancer progression has been well established at molecular level. However, whether and how IL-6 may play a role in prostate cancer risk and development is not well defined ...
Gang Liu +7 more
doaj +8 more sources
A nomogram based on radiomic features from peri-prostatic adipose tissue for predicting bone metastasis in first-time diagnosed prostate cancer patients [PDF]
Purpose To evaluate a radiomics-based nomogram using peri-prostatic adipose tissue (PPAT) features for predicting bone metastasis (BM) in newly diagnosed prostate cancer (PCa) patients.Methods A retrospective study of 151 PCa patients (October 2010 ...
Bohao Liu +9 more
doaj +5 more sources
Peri-Prostatic Adipocyte-Released TGFβ Enhances Prostate Cancer Cell Motility by Upregulation of Connective Tissue Growth Factor [PDF]
Periprostatic adipose tissue (PPAT) has emerged as a key player in the prostate cancer (PCa) microenvironment. In this study, we evaluated the ability of PPAT to promote PCa cell migration, as well as the molecular mechanisms involved.
Evelina La Civita +10 more
doaj +7 more sources
Fatty acid profile in peri-prostatic adipose tissue and prostate cancer aggressiveness in African–Caribbean and Caucasian patients [PDF]
Genetic and nutritional factors have been linked to the risk of aggressive prostate cancer (PCa). The fatty acid (FA) composition of peri-prostatic adipose tissue (PPAT), which reflects the past FA intake, is potentially involved in PCa progression.
Figiel, Sandy +22 more
core +9 more sources
MRI-Derived Apparent Diffusion Coefficient of Peri-Prostatic Adipose Tissue Is a Potential Determinant of Prostate Cancer Aggressiveness in Preoperative Setting: A Preliminary Report. [PDF]
Background: The aim of this study was to test the association between periprostatic adipose tissue (PPAT)—apparent diffusion coefficient (ADC) value recorded at multiparametric magnetic resonance imaging (mpMRI) and determinants of prostate cancer (PCa) aggressiveness in the preoperative setting.
Tafuri A +23 more
europepmc +3 more sources
Peri‐prostatic adipose tissue: the metabolic microenvironment of prostate cancer [PDF]
Emerging data have linked certain features of clinical prostate cancer ( PC a) to obesity and, more specifically, increased adiposity. Whereas the large number of clinical studies and meta‐analyses that have explored the associations between PC a and ...
Nassar, Z. +6 more
openaire +5 more sources
Exploring the Role of a Lifestyle Intervention on Peri-Prostatic Adipose Tissue and Fat Metabolism in Men with Prostate Cancer [PDF]
Zevitz J +8 more
europepmc +2 more sources
Fatty Acid Metabolism Reprogramming in Advanced Prostate Cancer
Prostate cancer (PCa) is a carcinoma in which fatty acids are abundant. Fatty acid metabolism is rewired during PCa development. Although PCa can be treated with hormone therapy, after prolonged treatment, castration-resistant prostate cancer can develop
Huan Xu +6 more
doaj +1 more source
Treatment of lipomas and diffuse lipomatosis with NDYAG 1064 NM laser and their impact on the quality of life [PDF]
Lipomas, the most common type of benign tumours, are generally developed from adipose tissue and present an incidence of 2.1 per 1000 inhabitants. In addition to lipomas, at least three other maladies of the adipose tissue lead patients to consult a ...
Andronache, Liliana Florina +5 more
core +3 more sources

