Results 31 to 40 of about 478,697 (222)
Genetic and non-genetic determinants of aggression in combat sports
Open Life Sciences, 2014 Human aggression/impulsivity-related traits are influenced by complex genetic and non-genetic factors. The aggression/anxiety relationship is controlled by highly conserved brain regions including the amygdala, hypothalamus and periaqueductal gray of the
Gronek Piotr +2 more
doaj +1 more source
A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety
Advanced Science, EarlyView.Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao +8 more
wiley +1 more source
Interactions between the lateral hypothalamus and the periaqueductal gray [PDF]
The Journal of Neuroscience, 1988 Anatomical and physiological experiments were conducted to characterize the interactions between the lateral hypothalamus (LH) and the periaqueductal gray (PAG) and to determine the role of neurotensin in their interaction. Anatomical studies using injection of Phaseolus vulgaris leucoagglutinin into the LH showed an extensive projection to the ...
M M, Behbehani, M R, Park, M E, Clement
openaire +2 more sources
Frontiers in Neuroscience, 2015 Sexual behavior is suppressed by various types of stressors. We previously demonstrated that an alarm pheromone released by stressed male Wistar rats is a stressor to other rats, increases the number of mounts needed for ejaculation, and decreases the ...
Tatsuya eKobayashi +3 more
doaj +1 more source
Functional organization of the midbrain periaqueductal gray for regulating aversive memory formation
Molecular Brain, 2021 Innately aversive experiences produce rapid defensive responses and powerful emotional memories. The midbrain periaqueductal gray (PAG) drives defensive behaviors through projections to brainstem motor control centers, but the PAG has also been ...
Li-Feng Yeh +2 more
doaj +1 more source
Advanced Science, EarlyView.RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan +8 more
wiley +1 more source
Enkephalinergic Neurons in the Periaqueductal Gray and Morphine Withdrawal
Japanese Journal of Pharmacology, 2000 The effects of opioid (e.g., morphine) withdrawal on levels of endogenous opioid peptides and their mRNA in the various brain regions have been studied. However, the role of this opioidergic mechanism in the mediation of opioid withdrawal is not fully understood.
Fukunaga, Yuko, Kishioka, Shiroh
openaire +3 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness +11 more
wiley +1 more source
Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray
Nature Communications, 2019 The supraspinal mechanisms involved in itch specific sensation are not well understood. Here the authors identify a subpopulation of neurons in the periaqueductal gray that modulate chronic itch in ...
Vijay K. Samineni +4 more
doaj +1 more source
COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad +7 more
wiley +1 more source