Results 241 to 250 of about 86,775 (289)

Multi‐Omics Data Reveal Estrogen‐Driven Dysregulation and Stromal‐Epithelial Signaling Alterations in Endometrial Polyps

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
Single‐cell transcriptomic profiling reveals that endometrial polyps arise from estrogen‐driven disruption of stromal‐epithelial signaling. Stromal cells exhibit enhanced WNT, IGF, and VEGF pathways, promoting epithelial proliferation and vascular remodeling.
Tingwei Chen, Bo Zhang, Zhengli Zhou, Naixue Yang, Ting Liu, Huimei Zhang, Yu Yin, Xiaomei Wu, Xiaozhuo Li, Tao Yu, Xiaodie Wang, Tianqing Li, E. Dong   +12 more
wiley   +1 more source

The regulation of placental pericyte function through transforming growth factor β-1 signalling. [PDF]

Sci Rep
MacPhee CA, Natale BV, Noordhof C, Wang S, Lima PDA, Natale DRC.   +5 more
europepmc   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

High Burden of Premature Ventricular Contractions Upregulates Transcriptional Markers of Inflammation and Promotes Adverse Cardiac Remodeling Linked to Cardiomyopathy. [PDF]

Circ Arrhythm Electrophysiol
Medina-Contreras JML, Balderas-Villalobos J, Gomez-Arroyo J, Hayles J, Kaszala K, Tan AY, Samsó M, Huizar JF, Eltit JM.   +8 more
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Stromal cells contribute to progression, recurrence, and metastasis in oral squamous cell carcinoma: a call for therapy. [PDF]

J Transl Med
Hao J, Zakershahrak M, Ly P, Le AD, Yu W, Gates JC, Chen C.   +6 more
europepmc   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Elucidating a Myofibroblast-dominated Fibrotic Niche in Crohn's Disease-associated Fibrostenosis Through High-resolution Spatial Transcriptomics. [PDF]

Cell Mol Gastroenterol Hepatol
Zhang D, Zou X, He M, Sun S, Yu A, Shi J, Ouyang T, Lin X, Yang H, Bai L, Sun K, Shi J, Wu F, Xie W, Li J, Xie F.   +15 more
europepmc   +1 more source