Results 281 to 290 of about 106,411 (380)

Vessel‐associated microglia are differentially activated and distributed in relation to systemic infection and Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
This post‐mortem study revealed an increased density of vessel‐associated microglia (VAM) in the temporal lobe in systemic infection and Alzheimer's disease. VAM density was related to brain cytokine levels and markers of cerebrovascular dysfunction and BBB leakage indicating that activated VAM contributes to neurovascular injury in Alzheimer's disease.
Oliver Milner   +5 more
wiley   +1 more source

Reviewer #1 (Public review): The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke

open access: gold
Tingbo Li   +16 more
openalex   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

open access: yesBrain Pathology, EarlyView.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong   +8 more
wiley   +1 more source

Quantifying Capillary Pericytes In Vivo Links Them to Retinal Vascular Leakage and Potentially Albuminuria: A Pilot Study in Diabetes. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Decker NL   +5 more
europepmc   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

open access: yesBrain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato   +15 more
wiley   +1 more source

PRRX1 Orchestrates Pericyte-Myofibroblast Transition in Pathological Retinal Fibrosis. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Meng Z   +10 more
europepmc   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

open access: yesCell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song   +4 more
wiley   +1 more source

Histone and non-histone (de)acetylation impact on the blood-brain barrier. [PDF]

open access: yesFluids Barriers CNS
Melo M   +3 more
europepmc   +1 more source

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