Results 61 to 70 of about 106,411 (380)

Calcium Signalling in Pericytes [PDF]

open access: yesJournal of Vascular Research, 2014
Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists of arteriolar and venular networks located upstream and downstream of the capillaries.
Theodor, Burdyga, Lyudmyla, Borysova
openaire   +2 more sources

Immune regulation by pericytes: modulating innate and adaptive immunity

open access: yesFrontiers in Immunology, 2016
Pericytes are mural cells that surround endothelial cells in small blood vessels. Pericytes have traditionally been credited with structural functions, being essential for vessel maturation and stabilization.
Rocio Navarro   +3 more
doaj   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

open access: yes, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E.   +3 more
core   +2 more sources

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Transcriptomic characterization of lung pericytes in systemic sclerosis-associated pulmonary fibrosis

open access: yesiScience
Summary: Systemic sclerosis (SSc) is a chronic disease characterized by fibrosis and vascular abnormalities in the skin and internal organs, including the lung.
Ludivine Renaud   +4 more
doaj   +1 more source

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

open access: yes, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G   +4 more
core   +1 more source

Pericytes synthesize renin

open access: yesWorld Journal of Nephrology, 2013
To investigate renin expression in pericytes during normal kidney development and after deletion of angiotensinogen, the precursor for all angiotensins.We examined the distribution of renin expressing cells by immunoshistochemistry in the interstitial compartment of wild type (WT) and angiotensinogen deficient (AGT -/-) mice at different developmental ...
Alison C, Berg   +4 more
openaire   +2 more sources

Pericytes modulate endothelial sprouting [PDF]

open access: yesCardiovascular Research, 2013
Angiogenic sprouts arise from microvessels formed by endothelial cells (ECs) invested by pericytes (PCs). The aim of this study was to examine the role of PCs in angiogenic sprouting, an understudied phenomenon.We adapted a human EC spheroid model to examine PC effects on vascular endothelial growth factor-A-induced EC sprouting in vitro by using Bcl-2-
William G, Chang   +4 more
openaire   +2 more sources

PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]

open access: yes, 2019
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit   +7 more
core   +1 more source

Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes

open access: yesCell Transplantation, 2020
Pericytes possess high multipotent features and cell plasticity, and produce angiogenic and neurotrophic factors that indicate their high regenerative potential.
Vyacheslav Ogay   +15 more
doaj   +1 more source

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