Results 11 to 20 of about 4,318 (158)
Isosorbide Concentration in Perilymph of the Guinea Pig After Oral Administration Versus That After Round Window Perfusion [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesThe aims of this study were to investigate the feasibility of isosorbide delivery into perilymph through the round window membrane (RWM), and to compare the intracochlear isosorbide concentration in perilymph after oral administration (PO ...
Minbum Kim, Kyung Hee Do, Kyu-Sung Kim
doaj +1 more source
Bioinformatic Analysis of the Perilymph Proteome to Generate a Human Protein Atlas
Frontiers in Cell and Developmental Biology, 2022 The high complexity of the cellular architecture of the human inner ear and the inaccessibility for tissue biopsy hampers cellular and molecular analysis of inner ear disease.
Alina van Dieken +8 more
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BMC Medical Imaging, 2021 Background Non-contrast FLAIR revealed increased signal within the inner ear in patients with vestibular schwannoma, which is generally assumed to occur in the perilymph; however, the majority of previous studies did not differentiate between the ...
Iichiro Osawa +7 more
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Frontiers in Neurology, 2022 We evaluated the inner ear distribution of 17O-labeled saline administered to the human tympanic cavity. Magnetic resonance imaging was performed after intratympanic administration in five healthy volunteers and one patient with cochlear endolymphatic ...
Tadao Yoshida +10 more
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Noise-Induced Perilymph Fistula [PDF]
Ear, Nose & Throat Journal, 2006 Perilymph fistulae are difficult to diagnose because they present with a wide variety of signs and symptoms, they are associated with many etiologies, and they often mimic other conditions. In this article, we describe a case of perilymph fistula that featured one of its more rare causes: acoustic trauma—specifically, damage from a loud blast from the
Brian, Kung, Robert T, Sataloff
openaire +2 more sources
The proteome of perilymph in patients with vestibular schwannoma. A possibility to identify biomarkers for tumor associated hearing loss? [PDF]
PLoS ONE, 2018 BACKGROUND:Due to the surrounding bone, the human inner ear is relatively inaccessible and difficult to reach for cellular and molecular analyses. However, these types of investigations are needed to better understand the etiology, pathophysiology and ...
Jesper Edvardsson Rasmussen +4 more
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Sonoporation of the Round Window Membrane on a Sheep Model: A Safety Study
Pharmaceutics, 2023 Sonoporation using microbubble-assisted ultrasound increases the permeability of a biological barrier to therapeutic molecules. Application of this method to the round window membrane could improve the delivery of therapeutics to the inner ear.
Sandrine Kerneis +10 more
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Severe self-limiting acute bilateral hearing loss following a low dose of methylphenidate for ADHD treatment: A case report. [PDF]
PCN RepPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Zandifar A, Badrfam R.
europepmc +2 more sources
Frontiers in Neurology, 2020 Glucocorticoids are used intra-operatively in cochlear implant surgeries to reduce the inflammatory reaction caused by insertion trauma and the foreign body response against the electrode carrier after cochlear implantation.
Arne Liebau +9 more
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Proteome of normal human perilymph and perilymph from people with disabling vertigo.
PLoS ONE, 2019 The vast majority of hearing loss, the most common sensory impairment, and vertigo, which commonly causes falls, both reflect underlying dysfunction of inner ear cells.
Hsiao-Chun Lin +4 more
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