Results 51 to 60 of about 4,318 (158)

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

open access: yesJournal of Anatomy, EarlyView.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu   +9 more
wiley   +1 more source

The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency. [PDF]

open access: yesPLoS ONE, 2015
This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston ...
Martin Grossöhmichen   +4 more
doaj   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

open access: yesThe Anatomical Record, Volume 309, Issue 4, Page 912-929, April 2026.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit   +6 more
wiley   +1 more source

Intralabyrinthine Penetrating Ventilation Tube with Preservation of Hearing: An Unusual Clinical Situation

open access: yesInternational Archives of Otorhinolaryngology, 2015
Introduction Traumatic perilymphatic fistula is not a rare event with regards to sport activities or traffic accident. However, iatrogenic damage to the inner ear can occur following the common use of grommets and ventilation tube insertion.
Tantely Razafimahefa Raoelina   +3 more
doaj   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot   +2 more
wiley   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu   +8 more
wiley   +1 more source

β-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph

open access: yesGMS German Medical Science, 2005
Objective: Beta-trace protein (β-TP) has been analysed in human cerebrospinal fluid (CSF) and other body fluids. Beta-trace protein is a very sensitive and specific clinical marker and can confirm reliably the presence of CSF in patients with a suspected
Nekic, Marko   +3 more
doaj  

Cochlear Implantation and Facial Nerve Stimulation: Clinical and Anatomic Correlations

open access: yesThe Laryngoscope, Volume 136, Issue 3, Page 1193-1203, March 2026.
One rare complication of cochlear implantation (CI) is facial nerve stimulation (FNS) and in this study the location and insertion depths for electrode contacts causing FNS was analyzed, and the anatomical variance of the human facial nerve canal (FNC) was explored to elucidate the mechanisms underlying FNS.
Karin Hallin   +4 more
wiley   +1 more source

Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1253-1267, 1 March 2026.
Abstract The pre‐hearing mouse cochlea undergoes critical periods of spontaneous Ca2+‐dependent activity that spreads across non‐sensory supporting cells and inner hair cells (IHCs). These signals have been shown to regulate not only the refinement of neural circuits along the auditory pathway towards functional maturity, but also the maturation of the
Francesca De Faveri   +2 more
wiley   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

open access: yesAdvanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck   +4 more
wiley   +1 more source

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