Creation of a Retinoblastoma Registry in a Resource‐Limited Country in Sub‐Saharan Africa
ABSTRACT Background Retinoblastoma (RB) is the most common ocular tumor in young children, originating from the developing retina, with the burden remaining higher in regions of low socio‐demographic index. A registry of RB is essential for creating effective referral networks for evaluating treatment patterns and contributing to the global pool of ...
Benjamin Abaidoo +23 more
wiley +1 more source
A central review of histopathology reports after breast cancer neoadjuvant chemotherapy in the neo-tango trial [PDF]
Background: Neo-tAnGo, a National Cancer Research Network (NCRN) multicentre randomised neoadjuvant chemotherapy trial in early breast cancer, enroled 831 patients in the United Kingdom.
K Walland +25 more
core +2 more sources
Thyroid Dysfunction Following Conventional Anthracycline- and Taxane-based Chemotherapy for Breast Cancer [PDF]
Although thyroid disorders induced by immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) have attracted much attention, little research has been done on thyroid dysfunction in conventional cancer treatment containing anthracyclines
Nishio, Miki +9 more
core +1 more source
Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma [PDF]
BACKGROUND: We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with advanced ovarian cancer. The results are compared with that of a similar assay used
Pauline A Whitehouse +36 more
core +2 more sources
Periocular recognition under expression variation using Higher Order Spectral features
Periocular recognition promises attractive trade-off between iris recognition and face recognition because it provides a longer range of imaging than iris and could achieve a higher recognition performance than face.
Faisal AlGashaam +7 more
core +1 more source
ABSTRACT Background and Aims Standard management of dry eye disease (DED) relies on artificial tears, anti‐inflammatory therapy, and punctal occlusion in selected cases. However, some patients continue to report persistent symptoms. The present article reviewed the efficacy of Botulinum Toxin A (BTX‐A) for DED that remained symptomatic after these ...
Mirsaeed Abdollahi +6 more
wiley +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Chemotherapy effects on brain glucose metabolism at rest [PDF]
Background: A growing number of studies reports that chemotherapy may impair brain functions inducing cognitive changes which can persist in a subset of cancer survivors.
Riccardo Torta +14 more
core
Multivariate analysis of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma: data from the INC-EU Prospective Observational European Neutropenia Study [PDF]
Summary Myelosuppression, particularly febrile neutropenia (FN), are serious dose-limiting toxicities that occur frequently during the first cycle of chemotherapy.
Impact of Neutropenia in Chemotherapy-European Study Group (INC- +26 more
core +1 more source

