Results 71 to 80 of about 10,499,951 (250)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Incubation Period: Not well determined; may be as short as 1-3 days.

open access: yes, 2014
Presumably until discharges of the mouth and nose no longer contain virulent pneumococci in significant numbers. Penicillin will render patients with susceptible strains noninfectious within 24-48 hours.
Infectious Period
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Analysis of different approaches to the calculation and design of road structures from corrugated metal

open access: yesДороги і мости
ntroduction. In order to improve the design methodology, particularly in the calculation of transport construction objects made of metal corrugated structures (MCS) with increased hole size (small bridges and arch-shaped overpasses, drainage pipes under ...
Volodymyr Abramov
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Results of the age-period-cohort model adjusted for cervical cancer mortality according to the period effect and states of the Northeast, Brazil, 1980–2014.

open access: yes, 2020
Results of the age-period-cohort model adjusted for cervical cancer mortality according to the period effect and states of the Northeast, Brazil, 1980–2014.
Gilcilene Pretta Cani Ribeiro (8468679)   +9 more
core   +1 more source

Another 'futile quest'? A simulation study of Yang and Land's Hierarchical Age-Period-Cohort model [PDF]

open access: yes, 2013
Background: Whilst some argue that a solution to the age-period-cohort (APC) 'identification problem' is impossible, numerous methodological solutions have been proposed, including Yang and Land's Hierarchical-APC (HAPC) model: a multilevel model ...
Bell, Andrew   +7 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Multiplexing of fiber-optic long-period grating-based interferometric sensors [PDF]

open access: yes, 2007
Two long-period gratings (LPGs) fabricated in series in an optical fiber form a Mach-Zehnder interferometer, producing a sinusoidal channelled spectrum within the characteristic LPG attenuation bands, which has the appearance of an interference fringe ...
Tatam, Ralph P.   +2 more
core   +1 more source

Theoretical and methodological foundations of pedagogical interaction of the educational process participants [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
Theoretical and methodological foundations of pedagogical interaction of the educational process participants at the system of higher school in the XX century are investigated.
Gonchar O.V.
doaj  

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