Results 71 to 80 of about 17,637,970 (344)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Influences of different definitions of the winter NAO index on NAO action centers and its relationship with SST

Atmospheric and Oceanic Science Letters, 2019
Winter North Atlantic Oscillation (NAO) indexes from observations based on various winter durations are compared. Results show that there are significant differences in the interannual and decadal variations of these NAO indexes. For the same data source,
Yujie JING, Yangchun LI, Yongfu XU, Guangzhou FAN   +3 more
doaj   +1 more source

Long period planets from dynamical relaxation

, 2009
Recent imaging campaigns indicate the likely existence of massive planets (~ 1-10 MJ) on ~1000 year orbits about a few percent of stars. Such objects are not easily explained in most current planet formation models. In this Letter we use ensembles of 100
Adams, Beuzit, Biller, Caleb Scharf, Chatterjee, Dong, Ford, Gaudi, Higuchi, Hollenbach, Ida, Juric, Kristen Menou, Lafrenière, Masciadri, Matsumura, Matzner, Mohanty, Nielsen, Oppenheimer, Papaloizou, Rafikov, Raymond, Thommes, Veras   +24 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Methodology for practical calculation of arched road structures made of corrugated metal

Дороги і мости
Introduction. To spread the practice of transport construction of road structures made of corrugated metal under the embankment, which have long been and successfully used in different countries of the world instead of small and medium-sized bridges ...
Volodymyr Abramov
doaj   +1 more source

GLOBAL COMPETITION BETWEEN NORTH AND SOUTH [PDF]

Revista Română de Geografie Politică, 2017
The human-geographic regionalization is a landmark in the demarcation of territories that include populations of the same demographic, cultural or economic background.
Luca DIACONESCU
doaj  

The period of a classical oscillator

, 2004
We develop a simple method to obtain approximate analytical expressions for the period of a particle moving in a given potential. The method is inspired to the Linear Delta Expansion (LDE) and it is applied to a large class of potentials.
Amore P., Amore P., Amore P., Bender C. M., Drazin P. G., P Amore, R. A Sáenz, Weinberg S.   +7 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Supplement to the methodology for calculating dridge structures made of corrugated metal taking into account the condituons of fixing the structures to the foundation

Дороги і мости
Introduction. The results of research and developments on supplementing the methodology for calculating corrugated metal bridge structures on highways, taking into account the actual conditions of fastening structures to the foundation, are presented ...
Volodymyr Abramov
doaj   +1 more source